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Journal of Immunology Research
Volume 2015 (2015), Article ID 724982, 8 pages
http://dx.doi.org/10.1155/2015/724982
Research Article

Adaptation to Resistance Training Is Associated with Higher Phagocytic (but Not Oxidative) Activity in Neutrophils of Older Women

1Catholic University of Brasília, 71966-700 Brasília, DF, Brazil
2Federal University of Juiz de Fora, 36036-330 Governador Valadares, MG, Brazil
3University of Brasília, 70910-900 Brasília, DF, Brazil
4Paulista University, 70390-130 Brasília, DF, Brazil

Received 10 June 2015; Revised 28 August 2015; Accepted 10 September 2015

Academic Editor: Eileen Uribe-Querol

Copyright © 2015 João Bartholomeu-Neto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. J. Nicklas and T. E. Brinkley, “Exercise training as a treatment for chronic inflammation in the elderly,” Exercise and Sport Sciences Reviews, vol. 37, no. 4, pp. 165–170, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Giunta, “Is inflammaging an auto[innate]immunity subclinical syndrome?” Immunity & Ageing, vol. 3, article 12, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Aw, A. B. Silva, and D. B. Palmer, “Immunosenescence: emerging challenges for an ageing population,” Immunology, vol. 120, no. 4, pp. 435–446, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. O. D. T. Nóbrega, V. P. Faleiros, and J. L. Telles, “Gerontology in the developing Brazil: achievements and challenges in public policies,” Geriatrics and Gerontology International, vol. 9, no. 2, pp. 135–139, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Panda, A. Arjona, E. Sapey et al., “Human innate immunosenescence: causes and consequences for immunity in old age,” Trends in Immunology, vol. 30, no. 7, pp. 325–333, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. D. S. Senchina and M. L. Kohut, “Immunological outcomes of exercise in older adults,” Clinical Interventions in Aging, vol. 2, no. 1, pp. 3–16, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. R. D. Stout and J. Suttles, “Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes,” Immunological Reviews, vol. 205, no. 1, pp. 60–71, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Álvarez-Rodríguez, M. López-Hoyos, P. Muñoz-Cacho, and V. M. Martínez-Taboada, “Aging is associated with circulating cytokine dysregulation,” Cellular Immunology, vol. 273, no. 2, pp. 124–132, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Solana, R. Tarazona, I. Gayoso, O. Lesur, G. Dupuis, and T. Fulop, “Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans,” Seminars in Immunology, vol. 24, no. 5, pp. 331–341, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Córdova, F. Lopes-E-Silva Jr., A. S. Pires et al., “Long-term resistance training is associated with reduced circulating levels of IL-6, IFN-gamma and TNF-alpha in elderly women,” NeuroImmunoModulation, vol. 18, no. 3, pp. 165–170, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. M. D. Phillips, M. G. Flynn, B. K. McFarlin, L. K. Stewart, and K. L. Timmerman, “Resistance training at eight-repetition maximum reduces the inflammatory milieu in elderly women,” Medicine and Science in Sports and Exercise, vol. 42, no. 2, pp. 314–325, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. J. García, E. Bote, M. D. Hinchado, and E. Ortega, “A single session of intense exercise improves the inflammatory response in healthy sedentary women,” Journal of Physiology and Biochemistry, vol. 67, no. 1, pp. 87–94, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. C. Córdova, V. C. Silva, C. F. Moraes, H. G. Simões, and O. T. Nóbrega, “Acute exercise performed close to the anaerobic threshold improves cognitive performance in elderly females,” Brazilian Journal of Medical and Biological Research, vol. 42, no. 5, pp. 458–464, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. R. S. Paula, V. C. Souza, A. L. Benedet et al., “Dietary fat and apolipoprotein genotypes modulate plasma lipoprotein levels in Brazilian elderly women,” Molecular and Cellular Biochemistry, vol. 337, no. 1-2, pp. 307–315, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. D. A. Lipschitz, “Screening for nutritional status in the elderly,” Primary Care, vol. 21, no. 1, pp. 55–67, 1994. View at Google Scholar · View at Scopus
  16. M. J. Brekke, M. L. Brekke, E. S. Quiter, J. R. Peters, R. M. Mullis, and D. B. Hunninghake, “Appropriate days for measuring intake of dietary fat and cholesterol,” Annals of Nutrition and Metabolism, vol. 36, no. 5-6, pp. 318–327, 1992. View at Publisher · View at Google Scholar · View at Scopus
  17. P. M. Lührmann, B. M. Herbert, C. Gaster, and M. Neuhäuser-Berthold, “Validation of a self-administered 3-day estimated dietary record for use in the elderly,” European Journal of Nutrition, vol. 38, no. 5, pp. 235–240, 1999. View at Publisher · View at Google Scholar · View at Scopus
  18. S. T. Philippi, Tabela de composiçäo de alimentos: suporte para decisäo nutricional, Coronário, São Paulo, Brazil, 2002.
  19. W. J. Kraemer, A. Fry, N. Ratamess, and D. French, “Strength testing: development and evaluation of methodology,” in Physiological Assessment of Human Fitness, P. Maud and C. Foster, Eds., pp. 115–138, Human Kinetics, Champaign, Ill, USA, 1995. View at Google Scholar
  20. D. Agin, D. Gallagher, J. Wang, S. B. Heymsfield, R. N. Pierson Jr., and D. P. Kotler, “Effects of whey protein and resistance exercise on body cell mass, muscle strength, and quality of life in women with HIV,” AIDS, vol. 15, no. 18, pp. 2431–2440, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. M. I. Muniz-Junqueira, L. M. F. Peçanha, V. L. da Silva-Filho, M. C. de Almeida Cardoso, and C. E. Tosta, “Novel microtechnique for assessment of postnatal maturation of the phagocytic function of neutrophils and monocytes,” Clinical and Diagnostic Laboratory Immunology, vol. 10, no. 6, pp. 1096–1102, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. P. J. Lachmann and M. J. Hobart, “Complement genetics in relation to HLA,” British Medical Bulletin, vol. 34, no. 3, pp. 247–252, 1978. View at Google Scholar · View at Scopus
  23. B. H. Park, S. M. Fikrig, and E. M. Smithwick, “Infection and nitroblue-tetrazolium reduction by neutrophils: a diagnostic acid,” The Lancet, vol. 292, no. 7567, pp. 532–534, 1968. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Mahbub, A. L. Brubaker, and E. J. Kovacs, “Aging of the innate immune system: an update,” Current Immunology Reviews, vol. 7, no. 1, pp. 104–115, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. A. Desai, A. Grolleau-Julius, and R. Yung, “Leukocyte function in the aging immune system,” Journal of Leukocyte Biology, vol. 87, no. 6, pp. 1001–1009, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Ortega, E. Giraldo, M. D. Hinchado, L. Martín, J. J. García, and M. De La Fuente, “Neuroimmunomodulation during exercise: role of catecholamines as ‘stress mediator’ and/or ‘danger signal’ for the innate immune response,” NeuroImmunoModulation, vol. 14, no. 3-4, pp. 206–212, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. R. J. Simpson, T. W. Lowder, G. Spielmann, A. B. Bigley, E. C. LaVoy, and H. Kunz, “Exercise and the aging immune system,” Ageing Research Reviews, vol. 11, no. 3, pp. 404–420, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Yan, A. Kuroiwa, H. Tanaka, M. Shindo, A. Kiyonaga, and A. Nagayama, “Effect of moderate exercise on immune senescence in men,” European Journal of Applied Physiology, vol. 86, no. 2, pp. 105–111, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Sasaki, T. Matsuura, R. Takahashi et al., “Effects of regular exercise on neutrophil functions, oxidative stress parameters and antibody responses against 4-hydroxy-2-nonenal adducts in middle aged humans,” Exercise Immunology Review, vol. 19, pp. 60–71, 2013. View at Google Scholar · View at Scopus
  30. V. Hack, G. Strobel, M. Weiss, and H. Weicker, “PMN cell counts and phagocytic activity of highly trained athletes depend on training period,” Journal of Applied Physiology, vol. 77, no. 4, pp. 1731–1735, 1994. View at Google Scholar · View at Scopus
  31. K. Kowatari, T. Umeda, T. Shimoyama, S. Nakaji, Y. Yamamoto, and K. Sugawara, “Exercise training and energy restriction decrease neutrophil phagocytic activity in judoists,” Medicine and Science in Sports and Exercise, vol. 33, no. 4, pp. 519–524, 2001. View at Google Scholar · View at Scopus
  32. D. Baylis, D. B. Bartlett, H. P. Patel, and H. C. Roberts, “Understanding how we age: insights into inflammaging,” Longevity & Healthspan, vol. 2, article 8, 2013. View at Publisher · View at Google Scholar
  33. C. R. Gomez, V. Nomellini, D. E. Faunce, and E. J. Kovacs, “Innate immunity and aging,” Experimental Gerontology, vol. 43, no. 8, pp. 718–728, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. A. C. Shaw, D. R. Goldstein, and R. R. Montgomery, “Age-dependent dysregulation of innate immunity,” Nature Reviews Immunology, vol. 13, no. 12, pp. 875–887, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. M. Gleeson and N. Bishop, “Special feature for the Olympics: effects of exercise on the immune system: modification of immune responses to exercise by carbohydrate, glutamine and anti-oxidant supplements,” Immunology & Cell Biology, vol. 78, no. 5, pp. 554–561, 2000. View at Google Scholar
  36. A. Bosutti, G. Malaponte, M. Zanetti et al., “Calorie restriction modulates inactivity-induced changes in the inflammatory markers C-reactive protein and pentraxin-3,” Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 8, pp. 3226–3229, 2008. View at Publisher · View at Google Scholar · View at Scopus
  37. M. J. Drummond, K. L. Timmerman, M. M. Markofski et al., “Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults,” American Journal of Physiology—Regulatory Integrative and Comparative Physiology, vol. 305, no. 3, pp. R216–R223, 2013. View at Publisher · View at Google Scholar · View at Scopus
  38. N. Mathur and B. K. Pedersen, “Exercise as a mean to control low-grade systemic inflammation,” Mediators of Inflammation, vol. 2008, Article ID 109502, 6 pages, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. A. M. W. Petersen and B. K. Pedersen, “The anti-inflammatory effect of exercise,” Journal of Applied Physiology, vol. 98, no. 4, pp. 1154–1162, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. M. S. Fragala, A. R. Jajtner, J. R. Townsend et al., “Leukocyte IGF-1 receptor expression during muscle recovery,” Medicine & Science in Sports & Exercise, vol. 47, no. 1, pp. 92–99, 2015. View at Publisher · View at Google Scholar · View at Scopus
  41. W. J. Kraemer, K. Häkkinen, R. U. Newton et al., “Effects of heavy-resistance training on hormonal response patterns in younger vs. older men,” Journal of Applied Physiology, vol. 87, no. 3, pp. 982–992, 1999. View at Google Scholar · View at Scopus
  42. S. Bermon, P. Ferrari, P. Bernard, S. Altare, and C. Dolisi, “Responses of total and free insulin-like growth factor-I and insulin-like growth factor binding protein-3 after resistance exercise and training in elderly subjects,” Acta Physiologica Scandinavica, vol. 165, no. 1, pp. 51–56, 1999. View at Publisher · View at Google Scholar · View at Scopus
  43. R. G. de Souza Vale, R. D. de Oliveira, C. S. Pernambuco, Y. P. D. S. F. de Meneses, J. D. S. Novaes, and A. D. F. D. de Andrade, “Effects of muscle strength and aerobic training on basal serum levels of IGF-1 and cortisol in elderly women,” Archives of Gerontology and Geriatrics, vol. 49, no. 3, pp. 343–347, 2009. View at Publisher · View at Google Scholar · View at Scopus
  44. M. Orenstein and C. Friedenreich, “Review of physical activity and the IGF family,” Journal of Physical Activity & Health, vol. 1, no. 4, pp. 291–320, 2004. View at Google Scholar
  45. N. C. Bishop, A. K. Blannin, N. P. Walsh, P. J. Robson, and M. Gleeson, “Nutritional aspects of immunosuppression in athletes,” Sports Medicine, vol. 28, no. 3, pp. 151–176, 1999. View at Publisher · View at Google Scholar · View at Scopus