Aeromonas salmonicida Infection Only Moderately Regulates Expression of Factors Contributing to Toll-Like Receptor Signaling but Massively Activates the Cellular and Humoral Branches of Innate Immunity in Rainbow Trout (Oncorhynchus mykiss)

Figure 3

Relative levels of mRNAs encoding cytokines in selected immune organs of trout after infection with A. salmonicida. The relative number of mRNA copies (ordinate) encoding Il1b (triangles; full line), Tnf (diamonds; broken line), Il8 (squares; line-dot-line), Il10 (circles; dotted line), and Tgfb (hexagon; full gray line) is plotted against the time after infection (abscissa). Different tissues (a) spleen, (b) head kidney, (c) liver, and (d) thymus were collected from five individuals/time point. Values are given as mean ± SEM; the pertinent data are listed in Table 2. Note that the relative quantity is presented on a scale. Asterisks indicate significant differences with compared to the control group (0 h).

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