Table of Contents Author Guidelines Submit a Manuscript
Journal of Immunology Research
Volume 2016, Article ID 1343760, 6 pages
http://dx.doi.org/10.1155/2016/1343760
Research Article

Polymorphism rs3828903 within MICB Is Associated with Susceptibility to Systemic Lupus Erythematosus in a Northern Han Chinese Population

Yue-miao Zhang,1,2,3,4 Xu-jie Zhou,1,2,3,4 Fa-juan Cheng,1,2,3,4 Yuan-yuan Qi,1,2,3,4 Ping Hou,1,2,3,4 Ming-hui Zhao,1,2,3,4 and Hong Zhang1,2,3,4

1Renal Division, Peking University First Hospital, Beijing 100034, China
2Peking University Institute of Nephrology, Beijing 100034, China
3Key Laboratory of Renal Disease, Ministry of Health of China, Beijing 100034, China
4Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Peking University, Ministry of Education, Beijing 100034, China

Received 22 March 2016; Revised 5 June 2016; Accepted 9 June 2016

Academic Editor: Roberta Rizzo

Copyright © 2016 Yue-miao Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. S. H. Lim, S. J. Lee, B. M. Feldman et al., “Systematic review of the quality of prognosis studies in systemic lupus erythematosus,” Arthritis Care and Research, vol. 66, no. 10, pp. 1536–1541, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. C.-F. Kuo, M. J. Grainge, A. M. Valdes et al., “Familial aggregation of systemic lupus erythematosus and coaggregation of autoimmune diseases in affected families,” JAMA Internal Medicine, vol. 175, no. 9, pp. 1518–1526, 2015. View at Publisher · View at Google Scholar · View at Scopus
  3. J.-W. Han, H.-F. Zheng, Y. Cui et al., “Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus,” Nature Genetics, vol. 41, no. 11, pp. 1234–1237, 2009. View at Publisher · View at Google Scholar
  4. W. Yang, N. Shen, D.-Q. Ye et al., “Genome-wide association study in asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus,” PLoS Genetics, vol. 6, no. 2, Article ID e1000841, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. J. B. Harley, M. E. Alarcón-Riquelme, L. A. Criswell et al., “Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci,” Nature Genetics, vol. 40, no. 2, pp. 204–210, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. L. F. Barcellos, S. L. May, P. P. Ramsay et al., “High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions,” PLoS Genetics, vol. 5, no. 10, Article ID e1000696, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. R. A. Eagle and J. Trowsdale, “Promiscuity and the single receptor: NKG2D,” Nature Reviews Immunology, vol. 7, no. 9, pp. 737–744, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Yang, H. Wang, B. Ni et al., “Mutual activation of CD4+ T cells and monocytes mediated by NKG2D-MIC interaction requires IFN-gamma production in systemic lupus erythematosus,” Molecular Immunology, vol. 46, no. 7, pp. 1432–1442, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. V. Groh, A. Brühl, H. El-Gabalawy, J. L. Nelson, and T. Spies, “Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 16, pp. 9452–9457, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Allez, V. Tieng, A. Nakazawa et al., “CD4+NKG2D+ T cells in crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions,” Gastroenterology, vol. 132, no. 7, pp. 2346–2358, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Rodríguez-Rodero, S. González, L. Rodrigo et al., “Transcriptional regulation of MICA and MICB: a novel polymorphism in MICB promoter alters transcriptional regulation by Sp1,” European Journal of Immunology, vol. 37, no. 7, pp. 1938–1953, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. S. Rodriguez-Rodero, L. Rodrigo, J. L. Fdez-Morera et al., “MHC class I chain-related gene B promoter polymorphisms and celiac disease,” Human Immunology, vol. 67, no. 3, pp. 208–214, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. E. M. Tan, A. S. Cohen, J. F. Fries et al., “The 1982 revised criteria for the classification of systemic lupus erythrematosus,” Arthritis and Rheumatism, vol. 25, no. 11, pp. 1271–1277, 1982. View at Publisher · View at Google Scholar · View at Scopus
  14. V. Groh, S. Bahram, S. Bauer, A. Herman, M. Beauchamp, and T. Spies, “Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium,” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 22, pp. 12445–12450, 1996. View at Publisher · View at Google Scholar · View at Scopus
  15. G. M. Venkataraman, D. Suciu, V. Groh, J. M. Boss, and T. Spies, “Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D,” The Journal of Immunology, vol. 178, no. 2, pp. 961–969, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Watzl, “The NKG2D receptor and its ligands-recognition beyond the ‘missing self’?” Microbes and Infection, vol. 5, no. 1, pp. 31–37, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. S. González, A. López-Soto, B. Suarez-Alvarez, A. López-Vázquez, and C. López-Larrea, “NKG2D ligands: key targets of the immune response,” Trends in Immunology, vol. 29, no. 8, pp. 397–403, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. D. Nachmani, N. Stern-Ginossar, R. Sarid, and O. Mandelboim, “Diverse herpesvirus MicroRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells,” Cell Host and Microbe, vol. 5, no. 4, pp. 376–385, 2009. View at Publisher · View at Google Scholar · View at Scopus