CryJ-LAMP DNA Vaccines for Japanese Red Cedar Allergy Induce Robust Th1-Type Immune Responses in Murine Model

Figure 3

CryJ1-LAMP and CryJ2-LAMP Vaccines induce a strong Th1 cellular response. Vaccination protocol is described in Figure 2. At the end of study, freshly isolated splenocytes were treated with 1 μg/mL CryJ1 (a) or CryJ2 (b) protein for 48 hours. IL-4 and IFN-γ production were detected by ELISPOT. All data are shown as mean ± SEM. , , and .

(a)

(b)