Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model

Figure 5

Immunodetection of IgY-containing cells in normal and tumor ovaries in hens. (a) Few IgY-containing cells are seen in the normal ovary. (b-c) Ovarian tumors at early and late stages. More IgY-containing cells are seen in the tumor stroma. Only a few IgY-containing cells are seen to be infiltrating into the tumor. Although influx of IgY-containing cells into the tumor stroma increased with OVCA progression, intratumoral population of IgY-containing cells did not increase. Black and red arrows indicate the examples of stromal and intratumoral IgY-containing cells, respectively. Dotted lines indicate the tumor in the stroma. Other legends are similar to Figure 3; 40x.

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