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Journal of Immunology Research
Volume 2016, Article ID 9540975, 13 pages
http://dx.doi.org/10.1155/2016/9540975
Research Article

Luciferase mRNA Transfection of Antigen Presenting Cells Permits Sensitive Nonradioactive Measurement of Cellular and Humoral Cytotoxicity

1Division of Translational and Experimental Oncology, Department of Medicine III, Johannes Gutenberg University, Freiligrathstrasse 12, 55131 Mainz, Germany
2BioNTech Cell & Gene Therapies GmbH, An der Goldgrube 12, 55131 Mainz, Germany
3BioNTech AG, An der Goldgrube 12, 55131 Mainz, Germany
4Ganymed Pharmaceuticals AG, An der Goldgrube 12, 55131 Mainz, Germany

Received 15 September 2015; Accepted 10 December 2015

Academic Editor: Andrew Geall

Copyright © 2016 Tana A. Omokoko et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [2 citations]

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  • Ugur Sahin, Evelyna Derhovanessian, Matthias Miller, Björn-Philipp Kloke, Petra Simon, Martin Löwer, Valesca Bukur, Arbel D. Tadmor, Ulrich Luxemburger, Barbara Schrörs, Tana Omokoko, Mathias Vormehr, Christian Albrecht, Anna Paruzynski, Andreas N. Kuhn, Janina Buck, Sandra Heesch, Katharina H. Schreeb, Felicitas Müller, Inga Ortseifer, Isabel Vogler, Eva Godehardt, Sebastian Attig, Richard Rae, Andrea Breitkreuz, Claudia Tolliver, Martin Suchan, Goran Martic, Alexander Hohberger, Patrick Sorn, Jan Diekmann, Janko Ciesla, Olga Waksmann, Alexandra-Kemmer Brück, Meike Witt, Martina Zillgen, Andree Rothermel, Barbara Kasemann, David Langer, Stefanie Bolte, Mustafa Diken, Sebastian Kreiter, Romina Nemecek, Christoffer Gebhardt, Stephan Grabbe, Christoph Höller, Jochen Utikal, Christoph Huber, Carmen Loquai, and Özlem Türeci, “Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer,” Nature, 2017. View at Publisher · View at Google Scholar
  • Edward W. Green, Lukas Bunse, Matthias Bozza, Khwab Sanghvi, and Michael Platten, “TCR validation toward gene therapy for cancer,” 2019. View at Publisher · View at Google Scholar