Research Article

IFN-γ Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model

Figure 3

Reduced expression of ELOVL and CerS in FAg-induced dermatitis. Dermatitis was induced by FAg as described in Figure 1, and the expression of ELOVL and CerS isozymes was determined by quantitative RT-PCR. (a) Changes in the expression of ELOVL isozymes by repeated application of FAg. (b) Changes in the expression of CerS isozymes by repeated application of FAg. Data are values relative to control. All data are presented as in nine (FAg) or ten (vehicle) mice and are from one experiment representative of two independent experiments. Two-sided Student’s t-test was used for pair-wise comparisons. and .
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