Research Article
Immunogenic Evaluation of Ribosomal P-Protein Antigen P0, P1, and P2 and Pentameric Protein Complex P0-(P1-P2)2 of Plasmodium falciparum in a Mouse Model
Figure 8
IgG1/IgG2a humoral response after threefold immunization with the recombinant ribosomal P. falciparum proteins. Predominance of Th1 response was observed exclusively after the first Msp-119 immunization (a), whereas all P-proteins gave a Th1 response () (a–c). The results are the for three determinations of pooled sera from six mice in each group. Statistical difference between the IgG1 and IgG2a levels in each study group was evaluated with the Wilcoxon signed-rank test; #, ##.
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