Association of Neutrophil–Lymphocyte Ratio and the Presence of Neonatal Sepsis

Table 2

Clinical and demographic characteristics according to NLR tertiles.

Variables	First tertile (< 0.91) ()	First tertile (0.91-1.88) ()	Third tertile (> 1.88) ()
Age (days)	11.0 (7.0, 19.0)	8.0 (4.0, 13.0)^a	5.0 (3.0, 10.0)^bc	<0.001
Male, (%)	298 (60.4%)	290 (58.8%)	298 (60.3%)	0.846
PCT (ng/mL)	0.11 (0.09, 0.18)	0.16 (0.10, 0.31)^a	0.50 (0.21, 2.86)^bc	<0.001
hsCRP (mg/L)	0.7 (0.7, 0.7)	0.7 (0.7, 0.7)	0.7 (0.7, 15.53)^bc	<0.001
Biochemical parameters
TBIL (μmol/L)	258.9 (93.7, 335.3)	260.8 (126.2, 330.0)	191.2 (111.1, 278.3)^bc	<0.001
AST (U/L)	37.0 (29.1, 51.7)	36.1 (28.3, 48.3)	40.3 (29.3, 57.1)^c	0.009
ALT (U/L)	26.7 (21.4, 35.7)	25.5 (19.3, 33.1)^a	27.8 (21.0, 36.6)^c	0.005
TP (g/L)			^bc	<0.001
ALB (g/L)		^a	^bc	<0.001
UREA (mmol/L)	2.3 (1.4, 3.2)	2.4 (1.6, 3.9)^a	3.1 (2.1, 4.7)^bc	<0.001
CREA (μmol/L)	44.8 (37.2, 52.5)	48.8 (40.0, 58.1)^a	57.0 (43.1, 75.7)^bc	<0.001
UA (μmol/L)	130.3 (100.6, 159.9)	138.9 (104.5, 185.4)^a	170.1 (118.9, 253.5)^bc	<0.001
Clinical data
Control, (%)	91 (18.5%)	65 (13.2%)	32 (6.5%)	<0.001
Infection	197 (40.0%)	223 (45.2%)	135 (27.3.0%)^bc	<0.001
Sepsis	205 (41.6%)	205 (41.6%)	327 (66.2%)^bc	<0.001

Abbreviations as in Table 1. ^b for sepsis vs. control. ^c for sepsis vs. infection.