Research Article
MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin
Table 2
Related enzyme and carrier of pyruvate analyzed in this study.
| Gene | Description | Location |
| PDHA1 | Pyruvate dehydrogenase (lipoamide) alpha 1 | Mitochondrion matrix. | PDHB | Pyruvate dehydrogenase (lipoamide) beta | Mitochondrion matrix. | PDK4 | Pyruvate dehydrogenase kinase, isozyme 4 | Mitochondrion matrix. | PDHX | Pyruvate dehydrogenase complex, component X | Mitochondrion matrix. | MPC2 | Mitochondrial pyruvate carrier 2 | Mitochondrion inner membrane | PDK2 | Pyruvate dehydrogenase kinase, isozyme 2 | Mitochondrion matrix. | PDK1 | Pyruvate dehydrogenase kinase, isozyme 1 | Mitochondrion matrix. | PDK3 | Pyruvate dehydrogenase kinase, isozyme 3 | Mitochondrion matrix. | MPC1 | Mitochondrial pyruvate carrier 1 | Mitochondrion inner membrane | PC | Pyruvate carboxylase | Mitochondrion matrix. | PDP1 | Pyruvate dehydrogenase phosphatase catalytic subunit 1 | Mitochondrion matrix. | PDPR | Pyruvate dehydrogenase phosphatase regulatory subunit | Mitochondrion matrix. | PDHA2 | Pyruvate dehydrogenase (lipoamide) alpha 2 | Mitochondrion matrix. | PDP2 | Pyruvate dehydrogenase phosphatase catalytic subunit 2 | Mitochondrion matrix. | PKLR | Pyruvate kinase, liver and RBC | Mitochondrion |
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