Research Article
MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin
Table 3
Clinicopathological correlation of MPC1 expression in the Ren Ji CRC cohort.
| Clinicopathological feature | Expression of MPC1 | | Low | High | value ( test) |
| Age (years) | | | | <60 | 95 | 96 | 0.766 | ≥60 | 103 | 98 | | Gender | | | | Male | 112 | 120 | 0.287 | Female | 86 | 74 | | Metastasis | | | | Yes | 52 | 30 | 0.009 | No | 146 | 164 | | Lymph node invasion | | | | Yes | 106 | 75 | 0.003 | No | 91 | 119 | | Tumor size | | | | <5 cm | 99 | 108 | 0.388 | ≥5 cm | 94 | 86 | | TNM stage | | | | I | 15 | 20 | 0.001 | II | 58 | 92 | | III | 74 | 52 | | IV | 51 | 30 | | KRAS mutation | | | | Mutation | 33 | 40 | 0.246 | No mutation | 51 | 43 | |
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