Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2-Based Protein for Human Visceral Leishmaniasis Diagnosis

Table 3

Performance of the DTL-4-ELISA in samples from patients with visceral leishmaniasis and negative controls from different geographical regions in Brazil.

Locality	Sensitivity% ()	95% CI	Specificity% ()	95% CI
Aracaju, SE	100.00 (9)	65.54-100.00	91.67 (12)	62.47-100.00
Campo Grande, MS	97.26 (73)	89.98-99.82	100.00 (121)	96.30-100.00
Bauru, SP	100.00 (12)	71.80-100.00	100.00 (7)	59.56-100.00
Natal, RN	93.75 (16)	69.69-99.99	100.00 (29)	88.13-100.00
Piauí state	89.47 (57)	78.53-95.44	—	—
Total	94.61 (167)	89.94-97.28	99.41 (169)	96.39-99.99

SE: Sergipe state; MS: Mato Grosso do Sul state; SP: São Paulo state; RN: Rio Grande do Norte state; : number of samples; 95% CI: 95% confidence interval.