Journal of Immunology Research

Lymphocyte Differentiation and Effector Functions


Publishing date
15 Apr 2012
Status
Published
Submission deadline
15 Oct 2011

1Department of Immunology, University of São Paulo, São Paulo, Brazil

2Department of Medicine, Imperial College London, London SW7 2AZ, UK

3The Scripps Research Institute, Jupiter, FL 33458, USA

4Department of Immunology, Microbiology and Parasitology, Federal University of São Paulo, São Paulo, Brazil


Lymphocyte Differentiation and Effector Functions

Description

The main focus of this special issue will be on the different steps of lymphocyte development, terminal differentiation, activation, and effector function that ultimately influence the immune response. The special issue will become an international forum for researchers to summarize the most recent developments and ideas in the field, with a special emphasis given to the observational results obtained within the last five years.

Several types of microenvironmental stimuli can influence lymphocyte fate from development through differentiation into different effector cells with distinct biological properties. These stimuli transduce signals that terminate in changes in transcription factor activity, inducing a broad range of phenotypes. In this manner, diverse adaptive immune responses can be modulated. Potential topics include, but are not limited to:

  • Lymphopoiesis and developmental checkpoints
  • Lymphocyte activation and differentiation upon antigen presentation
  • Central and peripheral tolerance
  • Lymphocyte effector mechanisms in immunity to pathogens, transplantation, and tumor immunity
  • Immunodeficiency and autoimmunity disorders

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 510603
  • - Editorial

Lymphocyte Differentiation and Effector Functions

Niels Olsen Saraiva Camara | Ana Paula Lepique | Alexandre S. Basso
  • Special Issue
  • - Volume 2012
  • - Article ID 836485
  • - Review Article

The Effects of TLR Activation on T-Cell Development and Differentiation

Bo Jin | Tao Sun | ... | Anthony E. T. Yeo
  • Special Issue
  • - Volume 2012
  • - Article ID 163453
  • - Review Article

Mechanisms behind Functional Avidity Maturation in T Cells

Marina Rode von Essen | Martin Kongsbak | Carsten Geisler
  • Special Issue
  • - Volume 2012
  • - Article ID 678705
  • - Review Article

HEB in the Spotlight: Transcriptional Regulation of T-Cell Specification, Commitment, and Developmental Plasticity

Marsela Braunstein | Michele K. Anderson
  • Special Issue
  • - Volume 2012
  • - Article ID 849195
  • - Research Article

The Modulation of PPARγ1 and PPARγ2 mRNA Expression by Ciglitazone in CD3/CD28-Activated Naïve and Memory CD4+ T Cells

Mohd Nor Norazmi | Rafeezul Mohamed | ... | Nik Soriani Yaacob
  • Special Issue
  • - Volume 2012
  • - Article ID 731486
  • - Review Article

Myeloid-Derived Suppressor Cells Participate in Preventing Graft Rejection

Yan Wang | Xiaodong Gu | ... | Zongyou Chen
  • Special Issue
  • - Volume 2012
  • - Article ID 925135
  • - Review Article

CD4+T Cells: Differentiation and Functions

Rishi Vishal Luckheeram | Rui Zhou | ... | Bing Xia
  • Special Issue
  • - Volume 2012
  • - Article ID 238924
  • - Research Article

Improved Activation toward Primary Colorectal Cancer Cells by Antigen-Specific Targeting Autologous Cytokine-Induced Killer Cells

Claudia Schlimper | Andreas A. Hombach | ... | Ingo G. H. Schmidt-Wolf
  • Special Issue
  • - Volume 2012
  • - Article ID 239368
  • - Review Article

A Key Role for NF-κB Transcription Factor c-Rel in T-Lymphocyte-Differentiation and Effector Functions

Alexander Visekruna | Anton Volkov | Ulrich Steinhoff
  • Special Issue
  • - Volume 2012
  • - Article ID 467101
  • - Review Article

From Murine to Human Nude/SCID: The Thymus, T-Cell Development and the Missing Link

Rosa Romano | Loredana Palamaro | ... | Claudio Pignata
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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