Journal of Immunology Research

Inflammation in Cancer: Part of the Problem or Part of the Solution?


Status
Published

Lead Editor

1“Victor Babes” National Institute of Pathology, Bucharest, Romania

2University of Verona, Verona, Italy

3University of Pittsburgh, Pittsburgh, USA


Inflammation in Cancer: Part of the Problem or Part of the Solution?

Description

Although a process was described 2000 years ago first by Celsus and then by Galen, inflammation and its precise role in disease still are a subject of intense research. The immune system triggers an array of inflammatory reactions as a response to any exogenous and/or endogenous homeostasis disturbing factors. These processes are vital to preserve cells, tissues, and organ integrity, but as they comprise complex elements, regulation of this array of events is the main key for maintaining a normal physiological, efficient process. The regulatory mechanisms, some of them still unknown, need to balance the immune response. Thus, an insufficient response may cause immunodeficiency resulting in infection, cancer, and neurodegeneration.

As inflammation can be classified as either acute or chronic, these facets of the process can follow tumorigenesis. In the present special issue we intend to gather works that tackle these issues, namely, chronic inflammation that triggers/favours oncogenesis of solid tumors, on one hand. On the other hand, we intend to gather works that show the inflammation process as mechanism of efficient immune therapy in oncology.

We invite investigators to contribute to reviews and original papers describing recent findings in oncology field with focus on inflammation as part of the problem or part of the solution in tumor process/disease evolution.

Potential topics include but are not limited to the following:

  • Proteomics/immunoproteomics biomarkers for monitoring inflammation in skin cancer, brain cancer, and other types of tumors
  • The innate-adaptive immune systems interface in inflammation
  • Signaling inflammation-mediated events as tumorigenesis triggers
  • Inflammasomes in cancer
  • Inflammation and transcriptomics
  • New methodological approaches for inflammation evaluation in cancer
  • New avenues of immune-therapy in cancer
  • Personalized medicine through inflammatory status evaluation
  • Bioinformatics: main tool for human inflammasome approaches
  • Inflammaging as tumorigenesis trigger

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 5403910
  • - Editorial

Inflammation in Cancer: Part of the Problem or Part of the Solution?

Monica Neagu | Donato Zipeto | Iulia D. Popescu
  • Special Issue
  • - Volume 2019
  • - Article ID 4513108
  • - Research Article

Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications

Sorina Dinescu | Simona Rebeca Ignat | ... | Marieta Costache
  • Special Issue
  • - Volume 2018
  • - Article ID 5196023
  • - Research Article

Variation in Expression of Inflammation-Related Signaling Molecules with Profibrotic and Antifibrotic Effects in Cutaneous and Oral Mucosa Scars

Mihai Bucur | Octavian Dinca | ... | Ecaterina Ionescu
  • Special Issue
  • - Volume 2018
  • - Article ID 1061780
  • - Review Article

Mediators of Inflammation – A Potential Source of Biomarkers in Oral Squamous Cell Carcinoma

Mircea Tampa | Madalina Irina Mitran | ... | Simona Roxana Georgescu
  • Special Issue
  • - Volume 2018
  • - Article ID 6156757
  • - Research Article

CD47 Blockade Inhibits Tumor Progression through Promoting Phagocytosis of Tumor Cells by M2 Polarized Macrophages in Endometrial Cancer

Shenglan Gu | Ting Ni | ... | Yudong Wang
  • Special Issue
  • - Volume 2018
  • - Article ID 7134235
  • - Research Article

Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity

Anna Pedrinolla | Massimo Venturelli | ... | Massimo Lanza
  • Special Issue
  • - Volume 2018
  • - Article ID 8260742
  • - Review Article

Myokines as Possible Therapeutic Targets in Cancer Cachexia

Emilia Manole | Laura C. Ceafalan | ... | Alexandra E. Bastian
  • Special Issue
  • - Volume 2018
  • - Article ID 4625472
  • - Review Article

The Central Role of Inflammation Associated with Checkpoint Inhibitor Treatments

Cristina Vajaitu | Carmen Cristina Draghici | ... | Vlad Mihai Voiculescu
  • Special Issue
  • - Volume 2018
  • - Article ID 9208274
  • - Research Article

Differential Intestinal Mucosa Transcriptomic Biomarkers for Crohn’s Disease and Ulcerative Colitis

Maria Dobre | Elena Milanesi | ... | Mircea Mănuc
  • Special Issue
  • - Volume 2018
  • - Article ID 7819520
  • - Review Article

Preclinical and Clinical Therapeutic Strategies Affecting Tumor-Associated Macrophages in Hepatocellular Carcinoma

H. Degroote | A. Van Dierendonck | ... | L. Devisscher
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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