Journal of Immunology Research

Cellular Immunity-Pathogen Interactions in Infectious Diseases


Status
Published

1National Veterinary Laboratory, Islamabad, Pakistan

2Kirikkale University, Kirikkale, Turkey

3US University of Health Sciences, Bethesda, USA


Cellular Immunity-Pathogen Interactions in Infectious Diseases

Description

There is an ongoing equilibrium between infectious agents and their susceptible hosts. While challenge of immune-competent individuals to low pathogenic strains usually results in elimination of the infectious agent, the other host-pathogen matches generally produce clinical courses of the disease. Host cells usually respond to the injuries caused by the pathogens by either committing a suicide (apoptosis) or by acting as silent carriers and transmitting the disease to the other naïve cells (e.g., prevention of apoptosis, phagocytosis, and viral interference).

On the other hand, many pathogens produce certain enzymes or proteins, which lead to the increased cellular adhesion and invasion abilities and also increased pathogenicity. On the other hand, completion of full genome mapping in human and several animals allows the scientists to analyze host resistance genes against such a specific disease by the comparison of sick and healthy individuals’ bioinformatics data. This means that the next discovery will be the definition of host resistance genes and their relations with cellular immunity in infectious diseases.

Addressing and highlighting these topics and updating the currently available knowledge about the host cellular immune system and its defensive role played against the pathogens will not only help the readers to understand the underlying mechanisms but will also lead to the arousal of intriguing queries in developing various therapies. We invite authors to submit original research and review articles covering these crucial areas of immunology.

Potential topics include, but are not limited to:

  • Basic concepts of host-pathogen interactions (role of cellular immunity, cytokine response, acute phase proteins, immunophenotyping, etc.)
  • Immune resistance/immune evasion/immune suppression mechanisms in infectious diseases
  • Host-parasite interactions: viral, bacterial, protozoer, and so forth
  • Genetic resistance to infectious diseases/epigenetics/virulence determination
  • Pattern recognition receptors (RIG-I and Toll-like receptors)
  • Apoptotic and antiapoptotic mechanisms

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 739783
  • - Editorial

Cellular Immunity-Pathogen Interactions in Infectious Diseases

Muhammad Abubakar | Hasan T. Atmaca | ... | Oguz Kul
  • Special Issue
  • - Volume 2015
  • - Article ID 981328
  • - Review Article

Helicobacter pylori and T Helper Cells: Mechanisms of Immune Escape and Tolerance

Tiziana Larussa | Isabella Leone | ... | Francesco Luzza
  • Special Issue
  • - Volume 2015
  • - Article ID 895416
  • - Research Article

The Potential Role of Th9 Cell Related Cytokine and Transcription Factors in Patients with Hepatic Alveolar Echinococcosis

Tuerhongjiang Tuxun | Shadike Apaer | ... | Hao Wen
  • Special Issue
  • - Volume 2015
  • - Article ID 846348
  • - Research Article

The Interplay between Zinc, Vitamin D and, IL-17 in Patients with Chronic Hepatitis C Liver Disease

Randa Reda | Amal A. Abbas | ... | Doaa Zakaria
  • Special Issue
  • - Volume 2015
  • - Article ID 315957
  • - Review Article

Comparative Immune Response in Children and Adults with H. pylori Infection

Alireza Razavi | Nader Bagheri | ... | Hedaytollah Shirzad
  • Special Issue
  • - Volume 2015
  • - Article ID 639107
  • - Review Article

Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis

Marcos Vinicius da Silva | Monique Gomes Salles Tiburcio | ... | Carlo Jose Freire Oliveira
  • Special Issue
  • - Volume 2015
  • - Article ID 152741
  • - Research Article

Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis

Lucio Roberto Castellano | Laurent Argiro | ... | Virmondes Rodrigues
  • Special Issue
  • - Volume 2015
  • - Article ID 162639
  • - Research Article

Human Gene Expression in Uncomplicated Plasmodium falciparum Malaria

James M. Colborn | Joni H. Ylöstalo | ... | Donald J. Krogstad
  • Special Issue
  • - Volume 2015
  • - Article ID 178947
  • - Review Article

Immune Evasion Strategies of Trypanosoma cruzi

Ana Flávia Nardy | Célio Geraldo Freire-de-Lima | Alexandre Morrot
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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