Journal of Immunology Research

New Biomarkers of Innate and Adaptive Immunity in Infectious Diseases


Status
Published

Lead Editor

1University of Nevada, Reno, USA

2Université de Montréal, Saint-Hyacinthe, Canada

3US Centers for Disease Control and Prevention, Pretoria, South Africa


New Biomarkers of Innate and Adaptive Immunity in Infectious Diseases

Description

Infectious diseases remain the leading cause of morbidity in the world. In some respect, this situation persists because we still do not have good diagnostic biomarkers for many infectious agents. Latest advances in molecular biology and immunology resulted in a rapid expansion in the field of immune biomarkers in recent years. These biomarkers can help to provide early diagnosis, evaluate the efficacy of treatment, and improve the disease outcome. Emerging infections and rapid spread of the antibiotic resistant strains of bacteria make further search for biomarkers especially urgent. Recently, FDA addressed the issue of the need for immune biomarkers, where developing and approval of the new diagnostics were regarded as essential for improving treatment of infectious diseases. Current search for novel biomarkers includes correlation analysis between clinical presentation and genetic mutation, cytokines, receptors, and growth factors found in the host and/or infectious agent.

Despite extensive research, the need for novel biomarkers remains critical. For instance, little is known about immune biomarkers for such emerging infections as Ebola and Zika. There is an ongoing search for biomarkers of the immune dysfunction in HIV and severe dengue disease. Also, novel biomarkers for Cytomegalovirus and Mycobacterium tuberculosis promise to provide useful information on the response to infection.

For this special issue, we invite potential authors to contribute original manuscripts, clinical trial results, and reviews focused on genetic aberrations, cytokines, growth factors, and other small biologically active molecules as potential biomarkers in infectious disease.

Potential topics include but are not limited to the following:

  • Recent discoveries in biomarkers (genetics, proteomics, cytokines, growth factors, hormones, etc.) of infectious disease contributing to diagnosis, treatment, and prophylaxis
  • In vitro and in vivo studies aimed at identifying biomarkers of bacterial and viral pathogens
  • Transcriptome and proteome analysis of biomarkers related to infectious disease pathogenesis
  • Bioinformatics approaches aimed at characterizing biomarkers related to clinical presentation, severity, and treatment efficacy of infectious disease
  • Novel therapeutic approaches for treatment of infectious disease using novel and currently used biomarkers
  • Biomarkers of interaction of the bacterial and viral pathogens with immune system, evasion, and development of resistance

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 7047405
  • - Editorial

New Biomarkers of Innate and Adaptive Immunity in Infectious Diseases

Sergey Morzunov | Varough Deyde | Levon Abrahamyan
  • Special Issue
  • - Volume 2017
  • - Article ID 3054217
  • - Clinical Study

Cytokine Profile of Patients with Allergic Rhinitis Caused by Pollen, Mite, and Microbial Allergen Sensitization

Yury A. Tyurin | Svetlana A. Lissovskaya | ... | Albert A. Rizvanov
  • Special Issue
  • - Volume 2017
  • - Article ID 3940743
  • - Research Article

Immunomodulating and Revascularizing Activity of Kalanchoe pinnata Synergize with Fungicide Activity of Biogenic Peptide Cecropin P1

N. S. Zakharchenko | A. S. Belous | ... | A. A. Lebedeva
  • Special Issue
  • - Volume 2017
  • - Article ID 8493545
  • - Clinical Study

Association of Toll-Like Cell Receptors TLR2 (p.Arg753GLN) and TLR4 (p.Asp299GLY) Polymorphisms with Indicators of General and Local Immunity in Patients with Atopic Dermatitis

Yury A. Tyurin | Anton F. Shamsutdinov | ... | Irina D. Reshetnikova
  • Special Issue
  • - Volume 2017
  • - Article ID 2157247
  • - Research Article

Analysis of Serum Cytokines and Single-Nucleotide Polymorphisms of SOD1, SOD2, and CAT in Erysipelas Patients

Charles C. Emene | Irina E. Kravchenko | ... | Albert A. Rizvanov
  • Special Issue
  • - Volume 2017
  • - Article ID 8601063
  • - Research Article

Comparative Assessment of Cytokine Pattern in Early and Late Onset of Neonatal Sepsis

Kh. S. Khaertynov | S. V. Boichuk | ... | A. A. Rizvanov
  • Special Issue
  • - Volume 2017
  • - Article ID 4645701
  • - Research Article

Bactericide, Immunomodulating, and Wound Healing Properties of Transgenic Kalanchoe pinnata Synergize with Antimicrobial Peptide Cecropin P1 In Vivo

A. A. Lebedeva | N. S. Zakharchenko | ... | A. S. Belous
  • Special Issue
  • - Volume 2017
  • - Article ID 9829436
  • - Research Article

Serum Cytokine Levels and Their Relation to Clinical Features in Patients with Autoimmune Liver Diseases

Dilyara Akberova | Andrei P. Kiassov | Diana Abdulganieva
  • Special Issue
  • - Volume 2017
  • - Article ID 2412747
  • - Research Article

Evolution of the Immune Response against Recombinant Proteins (TcpA, TcpB, and FlaA) as a Candidate Subunit Cholera Vaccine

Neda Molaee | Ghasem Mosayebi | ... | Hamid Abtahi
  • Special Issue
  • - Volume 2016
  • - Article ID 8528270
  • - Research Article

High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica

Ekaterina V. Martynova | Aygul H. Valiullina | ... | Svetlana F. Khaiboullina
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision105 days
Acceptance to publication43 days
CiteScore3.330
Impact Factor3.404
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