Safety and Efficacy of High Power Shorter Duration Ablation Guided by Ablation Index or Lesion Size Index in Atrial Fibrillation Ablation: A Systematic Review and Meta-Analysis

Table 2

Procedural characteristics.

Study	Treatment group	CF sensing catheter/Agilis sheath	STSF catheter/Agilis sheath	Mapping system	Anterior/Posterior wall power	Local lesion endpoint	Ablation strategy
Leo et al. [11]	HPSD-LSI 1	+/+	−	EnSite	40 W	Target LSI of 5.5–6 at the LA anterior wall and 4 at the posterior wall	PVI ± line
	LPLD-LSI 1	+/+	−	EnSite	40 W/20 W	Target LSI of 5.5–6 at the LA anterior wall and 4 at the posterior wall	PVI ± line
	HPSD-LSI 2	+/+	−	EnSite	40 W	Target LSI of 5.5–6 at the LA anterior wall and 5 at the posterior wall	PVI ± line
	LPLD-LSI 2	+/+	−	EnSite	40 W/20 W	Target LSI of 5.5–6 at the LA anterior wall and 5 at the posterior wall	PVI ± line
Kaneshiro et al. [19]	HPSD-AI	−	+/−	CARTO	45–50 W	Target AI of 400 at the LA posterior wall	PVI ± line
	LPLD	+−/−	+−/−	CARTO	20–30 W	Duration at 10–30 s, CF 20–30 g	PVI ± line
Berte et al. [17]	HPSD-AI	−	+/+	CARTO	45 W/35 W	Target AI of 550 at the LA anterior wall and 300–400 at the posterior wall	PVI
	LPLD-AI	−	+/+	CARTO	35 W/25 W	Target AI of 550 at the LA anterior wall and 300–400 at the posterior wall	PVI
Okamatsu et al. [12]	HPSD-AI1	−	+/+−	CARTO	50 W/30–40 W	Target AI of 400 at the LA anterior wall and 260–360 at the posterior wall	PVI ± line ± box isolation ± CFAE
	LPLD-AI	−	+/+−	CARTO	30 W/20 W	Target AI of 400 at the LA anterior wall and 260–360 at the posterior wall	PVI ± line ± box isolation ± CFAE
	HPSD-AI2	−	+/+−	CARTO	40 W/30 W	Target AI of 400 at the LA anterior wall and 260–360 at the posterior wall	PVI ± line ± box isolation ± CFAE
Castrejon-Castrejon et al. [18]	HPSD50w-AI or LSI	+/+−	−	CARTO/ EnSite	50 W	LSI≥ 5, AI≥ 350 at the LA posterior wall and ≥450 in others	PVI ± line
	HPSD60w	+/+−	−	CARTO/EnSite	60 W	2–7 s	PVI ± line
	LPLD	+/+−	−	CARTO/EnSite	30 W/20–30 W	30–60 s	PVI ± line
Kyriakopoulou et al. [13]	HPSD-AI	+/−	−	CARTO	40 W	Target AI of 550 at the LA anterior wall and 300–400 at the posterior wall	PVI
	LPLD-AI	+/−	−	CARTO	35 W	Target AI of 550 at the LA anterior wall and 300–400 at the posterior wall	PVI
Dhillon et al. [10]	HPSD-AI	−	+/−	CARTO	40 W/30 W	Target AI of 450 at the LA anterior wall and 350 at the posterior wall	PVI ± line
	LPLD	+/−	−	CARTO	30 W/25 W	CF 20–30 g	PVI ± line

AI, ablation index; CF, contact force; CFAE, complex fractionated atrial electrogram; CTI, cava-tricuspid isthmus isolation; HPSD, high power shorter duration; LA, left atrial; LPLD, low power longer duration; LSI, lesion size index; PVI, pulmonary vein isolation; STSF, ThermoCool SmartTouch Surround Flow; SVCI, superior vena cava isolation.