Transcatheter Aortic Valve Replacement (TAVR) found its roots in treatment of severe aortic stenosis in patients with a high surgical risk. Recently, there is a trend to use TAVR in patients who are low and intermediate risk. Due to the increasing rate of TAVR use, data on outcomes and variables impacting outcomes continue to be of interest. Indeed, recently published research has focused on periprocedural antibiotic use, permanent pacemaker implantation rates, and cerebral embolic protection systems. The main issues facing TAVR use includes cost-benefit analyses, treatment of unexpected consequences of TAVR, and understanding risk factors for suboptimal outcomes.

The scope of this Special Issue includes prospective studies on TAVR outcomes. Our aims include dispersion of knowledge regarding management of post-procedural outcomes, variables associated with worse outcomes, strategies for subgroups of TAVR patients, and the impact of TAVR on comorbidities. We would especially welcome efforts to create national or international TAVR registries. Descriptions of technique for challenging cases are welcome.

Potential topics include but are not limited to the following:

• Impact of TAVR on quality of life metrics
• Outcomes of permanent pacemaker implantations and associated risk for revisions
• Management of permanent pacemaker implantation (such as postprocedural temporary pacemaker)
• Novel strategies taken to minimize ischemic strokes peri-procedurally
• Impact of TAVR on patients’ ability to address other chronic comorbidities
• Discussion of variables related to poor outcomes such as acute renal insufficiency or bleeding
• Trends of findings during post-procedural follow-up
• Long-term outcomes in patients who underwent TAVR
• Changes in medication management following TAVR
• Discussions on core measures for TAVR patients
• Investigations and descriptions of infected TAVR valves
• Management strategies of TAVR complicated by thrombus formation
• Data on previously unexplored subgroups of TAVR patients
• Management strategies of paravalvular leaks after TAVR
• Changes in physiologic parameters such as hemodynamics post-TAVR