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Journal of Nanomaterials
Volume 2013 (2013), Article ID 463732, 10 pages
Research Article

An Investigation of Optimum NLC-Sunscreen Formulation Using Taguchi Analysis

1Department of Chemical and Materials Engineering, Lunghwa University of Science and Technology, No. 300, Section 1, Wanshou Road, Guishan, Taoyuan 333, Taiwan
2Taiwan Shine Tide Biotech Co., 6F.-11, No. 1180, Zhongzheng Road, Zhonghe, New Taipei City 235, Taiwan
3Taiwan AC Scientific Inc., 6F.-5, No. 82, Section 2, Sin Sheng S. Road, Taipei 106, Taiwan

Received 9 April 2013; Accepted 1 August 2013

Academic Editor: Jie Huang

Copyright © 2013 Pao Chi Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study used three kinds of wax and three kinds of oil, with fixed mixture ratio including UV-blocking materials of ethylhexyl methoxycinnamate, oxybenzone, and avobenzone, and applied hot high-pressure homogenization process to prepare nanolipid sunscreen formulations. The measured particle size of the sunscreen formulations was 100~300 nm around PDI of 0.2 having a moderate polydisperse system. The distribution of zeta potential was −50 mV to −35 mV, showing a stable system. The UV light-absorbing range of 9 groups of sunscreen formulations was 275 nm~380 nm ranging within UVA and UVB. The rheological analysis found that the viscosity change is shear, thinning exhibiting colloid behavior. Taguchi analysis found that the optimum combinations are the carnauba wax and the blackcurrant oil combination for crystallinity and the beeswax and CPG oil for UV absorption. In addition, UV-blocking ability shows that the SPF was 51.5 and PFA was three stars for SU9 formulation. Finally, the effect of temperature on the properties of sunscreen formulations was also explored.