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Journal of Nanomaterials
Volume 2018, Article ID 9780489, 8 pages
Review Article

Heparin-Based Nanoparticles: An Overview of Their Applications

1Laboratorio de Investigación Interdisciplinaria, Área de Nanoestructuras y Biomateriales, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México (UNAM), Boulevard UNAM No. 2011, Predio El Saucillo y El Potrero, 37684 León, GTO, Mexico
2Centro de Investigaciones en Óptica, AP 1-948, 37150 León, GTO, Mexico

Correspondence should be addressed to Maria del Pilar Rodriguez-Torres; moc.liamg@serrot.zdr.ralip

Received 26 June 2017; Accepted 19 November 2017; Published 14 January 2018

Academic Editor: Faheem Ahmed

Copyright © 2018 Maria del Pilar Rodriguez-Torres et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This review deals with nanoparticles synthesized using heparin. Such nanoparticles have been widely studied since a long time ago, obtaining satisfactory outcomes. An outstanding aspect of these nanoparticles is that they possess good biocompatible characteristics, and since heparin is produced in the human body within the mast cells, this makes these nanoparticles useful for future applications like imaging, disease and cancer treatment, and antibacterial activity. They can also be used for applications that are not oriented directly to the medical and biological areas such as in the case of analyte detection in aqueous solution, although such studies are very few. These nanoparticles synthesis is mainly through wet chemistry methods, using heparin that could have been modified or not.