COX-2 Regulates the Proliferation and Apoptosis of Activated Hepatic Stellate Cells through CDC27

Table 3

Differential gene expression profiles between COX-2-shRNA-1 and sh-NC at 72 hours posttransfection.

	Oligo_id	Name	Ratio	Description
1	Rn30022454	—	6.1452	Tripartite motif-containing 65
2	Rn30006362	Purb	3.4474
3	R001746_01	Cxcl10	2.8634	Small inducible cytokine B10 precursor
4	Rn30020145	—	2.652
5	Rn30001057	Oasl1	2.6028	2-5-Oligoadenylate synthetase-like 1
6	Rn30005291	Cdc27	2.4796	Cell division cycle 27 homolog
7	Rn30006471	—	2.3552	PFTAIRE protein kinase 1
8	Rn30015483	Gbp4	2.3519	Similar to guanylate nucleotide-binding protein 4
9	Rn30021673	—	2.3392	¨C
10	R000595_01	Cx3cl1	2.3344	Fractalkine precursor
11	Rn30001055	Oasl1	2.3048	2-5-Oligoadenylate synthetase-like 1
12	Rn30002812	Enah	2.2328	Enabled homolog
13	Rn30018127	—	2.2025	Diaphanous homolog 1
14	Rn30024865	isg12(b)	2.2007	Putative ISG12(B) protein
15	Rn30025470	—	2.1365	RNA-binding motif protein 27
16	Rn30025880	—	2.0773	Topoisomerase (DNA) II beta-binding protein
17	Rn30021148	Ifit3	2.0594	Human interferon-inducible proteins
18	Rn30002530	Rfc1	2.035	VIP-receptor-gene repressor protein
19	Rn30006955	—	1.9683	Peptidyl-prolyl cis-trans isomerase G
20	Rn30024339	Gbf1	1.9515	Golgi-specific brefeldin A-resistance factor 1
21	Rn30015485	Gbp4	1.9459	Similar to guanylate nucleotide-binding protein 4
22	Rn30009903	Trp53	1.8363	Cellular tumor antigen p53
23	Rn30010375	—
24	Rn30006914	Loxl3	1.7087	Similar to lysyl oxidase-like 3
25	Rn30018257	Hsp90ab1	1.7047	Heat shock protein HSP 90-beta (HSP 84).
26	Rn30016830	Chd4	1.6964	Mi-2 autoantigen
27	Rn30021722	Apol9a	1.6932	¨C
28	Rn30015487	Gbp5	1.6803	Similar to guanylate-binding protein 5
29	Rn30009073	—	1.6721	¨C
30	Rn30008992	—	1.6509	WAS protein family, member 2
31	Rn30017948	Psmb10	1.6478	Proteasome subunit, beta type 10
32	Rn30005283	—	1.644	Rap1 interacting factor 1 homolog (yeast)
33	Rn30019336	Pogz	1.6139	Pogo transposable element with ZNF domain
34	Rn30023995	NIPBL	1.6115	PREDICTED: similar to delangin
35	Rn30021836	Olr1214	1.5675	Olfactory receptor Olr1214
36	R003169_01	Acsl6	1.5651	Long-chain-fatty-acid–CoA ligase 6
37	R004194_01	Zfp709	1.565	Zinc finger protein 14
38	Rn30004337	RGD1565597	1.5561	Similar to RIKEN cDNA 2210421G13
39	Rn30007454	—	1.5487	Complement receptor 2
40	Rn30003220	—	1.545	13-day embryo male testis cDNA
41	Rn30015924	Trub1	1.5415	TruB pseudouridine (psi) synthase homolog 1
42	Rn30019481	Gabpb2	1.5354	Transcription factor GABP beta 2-1 chain
43	Rn30009011	RGD1305500	1.5248	DNA segment, Chr 19, ERATO Doi 737
44	Rn30015486	Gbp5	1.5204	Guanylate-binding protein 5
45	Rn30015488	—	1.5197	Guanylate nucleotide-binding protein 2
46	R002891_01	Cyp2d4v1	1.5187	Cytochrome P450 2D18
47	Rn30016434	—	1.5155	RGD1310888-predicted protein
48	Rn30001002	—	1.5108
49	R001164_01	—	1.5085	Granzyme M precursor
50	Rn30023011	—	1.5073
51	Rn30000745	Hspa1b	0.6661	Heat shock 70 kDa protein 1A/1B
52	Rn30010844	—	0.6653
53	R002646_01	—	0.665
54	Rn30013433	Med31	0.6623	RNA polymerase II transcription subunit 31
55	Rn30003203	Dynlt3	0.6605	T-complex-associated testis-expressed 1-like
56	Rn30022044	—	0.6596	—
57	Rn30003825	Nt5c1b	0.6581	Retinol dehydrogenase 14
58	Rn30025065	P4ha2	0.6576	Procollagen-proline, 2-oxoglutarate-4-dioxygenase, alpha II polypeptide
59	Rn30000745	Hspa1b	0.6555	Heat shock 70 kDa protein 1A/1B
60	Rn30019963	—	0.6548	—
61	Rn30005770	Ero1l	0.6482	ERO1-like protein alpha precursor
62	Rn30024141	—	0.6465	¨C
63	Rn30019903	Rassf1	0.6464	Ras association domain family 1 isoform 2
64	Rn30003533	Dusp1	0.6461	Dual specificity protein phosphatase 1
65	Rn30020658	RGD1563649	0.6446	Similar to ORF4
66	Rn30006166	Pea15a	0.6435	Phosphoprotein enriched in astrocytes 15
67	Rn30012217	Arg1	0.6427	Arginase-1 (EC 3.5.3.1)
68	Rn30023334	—	0.6392
69	Rn30023867	Rnase1l2	0.6379
70	Rn30002222	Pgk1	0.6341	Phosphoglycerate kinase 1
71	R002211_01	Aldoc	0.6301	Fructose-bisphosphate aldolase C
72	Rn30002683	RGD1560553	0.6288	PREDICTED: similar to hypoxia-induced gene 1
73	Rn30018943	—	0.6233	DNA-3-methyladenine glycosylase
74	Rn30006243	—	0.619
75	Rn30025357	—	0.6154
76	Rn30000745	Hspa1b	0.6086	Heat shock 70 kDa protein 1A/1B
77	Rn30003851	Sh3kbp1	0.6013	SH3-domain kinase binding protein 1
78	Rn30000745	Hspa1b	0.5944	Heat shock 70 kDa protein 1A/1B
79	Rn30005084	LOC499742	0.5851	LRRGT00150.
80	Rn30000745	Hspa1b	0.5848	Heat shock 70 kDa protein 1A/1B
81	Rn30015841	Bnip3	0.581	BCL2/adenovirus E1B-interacting protein 3
82	Rn30014271	RGD1559815	0.5793	Da1-12
83	Rn30000745	Hspa1b	0.5732	Heat shock 70 kDa protein 1A/1B
84	Rn30000745	Hspa1b	0.5731	Heat shock 70 kDa protein 1A/1B
85	Rn30000745	Hspa1b	0.5706	Heat shock 70 kDa protein 1A/1B
86	Rn30000745	Hspa1b	0.5699	Heat shock 70 kDa protein 1A/1B
87	Rn30026196	Hist1h4m	0.5511	Histone H4.
89	Rn30000745	Hspa1b	0.545	Heat shock 70 kDa protein 1A/1B
90	Rn30024135	LOC499698	0.5425	C-reactive protein precursor.
91	Rn30000745	Hspa1b	0.5364	Heat shock 70 kDa protein 1A/1B
92	Rn30015672	Car9	0.51	Similar to carbonic anhydrase 9
93	Rn30004468	Upp1	0.4769	Uridine phosphorylase 1
94	Rn30014956	Plcd4	0.4744	Phospholipase C, delta 4
95	R001854_01	Ccl20	0.4709	Small inducible cytokine A20 precursor
96	Rn30022206	Dusp6	0.4411	Dual specificity protein phosphatase 6