Journal of Nanomaterials

Biocompatibility and Toxicity of Nanobiomaterials

Publishing date
20 Jul 2012
Submission deadline
02 Mar 2012

Lead Editor

1School of Biological Science and Medical Engineering, Beijing University of Aeronautics and Astronautics, Beijing, China

2Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University, Yongin-si, Republic of Korea

3Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA

4Department of Biomedical Materials and Engineering, Hokkaido University, Sapporo, Japan

Biocompatibility and Toxicity of Nanobiomaterials


Over the past decades, nanobiomaterials have played significant roles in the field of biomedical engineering and pharmaceutics. The wide variety of nanobiomaterials has encouraged their use in applications including drug delivery systems, imaging systems for diagnosis, tissue engineering, and dental/bone implant. For successful clinical applications, the investigations into biocompatibility and toxicity of nanobiomaterials are research interests of great significances.

To date, many trials have been performed to estimate in vitro and in vivo biocompatibility and toxicity of nanobiomaterials. Based on such preclinical evaluation of biocompatibility and toxicity, current research trends are focused on whether the nanobiomaterials induce toxic effects in human body. For example, some nanomaterials may be uptaken by phagocytic cells of the RES (reticuloendothelial system), to induce the production of reactive oxygen species and cause oxidative stress or preinflammatory cytotoxic activity in the lungs, liver, heart, and brain, etc.

We invite investigators to submit original research articles and review articles that inspire continuous efforts to understand the biocompatibility and toxicity of nanobiomaterials. We are particularly interested in articles describing novel nanobiomaterials design, nanobiomaterials/cell interaction, biocompatibility/toxicity testing protocol, as well as nanobiomaterials degradation. Potential topics include, but are not limited to:

  • Biocompatibility of nanobiomaterials
  • Toxicity of nanobiomaterials
  • Interaction between nanobiomaterials and cell/tissue
  • Effect of size, shape, and surface of nanobiomaterials on their biocompatibility and toxicity
  • Immunogenicity of nanobiomaterials
  • Challenges to overcome the toxicity of nanobiomaterials
  • Design of novel biocompatible and biodegradable nanobiomaterials
  • Instrumentation and technology to analyze toxicity of nanobiomaterials

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2012
  • - Article ID 746960
  • - Research Article

Control of In Vivo Transport and Toxicity of Nanoparticles by Tea Melanin

Yu-Shiun Chen | Yao-Ching Hung | ... | G. Steve Huang
  • Special Issue
  • - Volume 2012
  • - Article ID 731592
  • - Research Article

Biocompatibility of Nanoporous TiO2 Coating on NiTi Alloy Prepared via Dealloying Method

Jin Huang | Junqiang Wang | ... | Yubo Fan
  • Special Issue
  • - Volume 2012
  • - Article ID 939821
  • - Research Article

Noninvasive Evaluation of Injectable Chitosan/Nano-Hydroxyapatite/Collagen Scaffold via Ultrasound

Yan Chen | Songjian Li | ... | Bo Yu
  • Special Issue
  • - Volume 2012
  • - Article ID 384671
  • - Research Article

Biocompatible Single-Crystal Selenium Nanobelt Based Nanodevice as a Temperature-Tunable Photosensor

Yongshan Niu | Aimiao Qin | ... | Yubo Fan
  • Special Issue
  • - Volume 2012
  • - Article ID 401084
  • - Research Article

In Vitro Biocompatibility and Osteoblast Differentiation of an Injectable Chitosan/Nano-Hydroxyapatite/Collagen Scaffold

Yan Chen | Zhi Huang | ... | Bo Yu
  • Special Issue
  • - Volume 2012
  • - Article ID 714134
  • - Review Article

Nanotechnology-Based Therapies for Skin Wound Regeneration

Ilaria Tocco | Barbara Zavan | ... | Vincenzo Vindigni
  • Special Issue
  • - Volume 2012
  • - Article ID 452767
  • - Research Article

Evaluation on Cartilage Morphology after Intra-Articular Injection of Titanium Dioxide Nanoparticles in Rats

Jiangxue Wang | Yu Gao | ... | Yubo Fan
Journal of Nanomaterials
 Journal metrics
Acceptance rate49%
Submission to final decision69 days
Acceptance to publication29 days
Journal Citation Indicator0.310
Impact Factor2.986

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.