Identification of a Modified HOXB9 mRNA in Breast Cancer

Figure 2

Detection of mRNA and genomic DNA of HOXB9 in cell lines. (a) Both HOXB9n and HOXB9v transcripts were detected in breast cancer cell line mRNA (cDNA). (b) Sequencing confirmation of PCR product of Figure 2(a); SKBR3 (HOXB9n, upper column) and MCF10A (HOXB9v, lower column). (c) No genomic variation was detected in genomic DNA of breast cancer cell line genomic DNA. HOXB9v transcripts are commonly found in human breast cancer specimens.

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