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Journal of Ophthalmology
Volume 2015, Article ID 309510, 8 pages
http://dx.doi.org/10.1155/2015/309510
Research Article

Histological Characterization of the Dicer1 Mutant Zebrafish Retina

1Cornea Research Chair, Department of Optometry, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi Arabia
2Department of Life Sciences, Glasgow Caledonian University, Glasgow G4 0BA, UK

Received 29 August 2014; Accepted 29 October 2014

Academic Editor: Houbin Zhang

Copyright © 2015 Saeed Akhtar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. N. Kim, J. Han, and M. C. Siomi, “Biogenesis of small RNAs in animals,” Nature Reviews Molecular Cell Biology, vol. 10, no. 2, pp. 126–139, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Jinek and J. A. Doudna, “A three-dimensional view of the molecular machinery of RNA interference,” Nature, vol. 457, no. 7228, pp. 405–412, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Zhang, F. A. Kolb, L. Jaskiewicz, E. Westhof, and W. Filipowicz, “Single processing center models for human Dicer and bacterial RNase III,” Cell, vol. 118, no. 1, pp. 57–68, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. I. J. MacRae, K. Zhou, F. Li et al., “Structural basis for double-stranded RNA processing by Dicer,” Science, vol. 311, no. 5758, pp. 195–198, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Wienholds, M. J. Koudijs, F. J. M. Van Eeden, E. Cuppen, and R. H. A. Plasterk, “The microRNA-producing enzyme Dicer1 is essential for zebrafish development,” Nature Genetics, vol. 35, no. 3, pp. 217–218, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Grishok, A. E. Pasquinelli, D. Conte et al., “Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing,” Cell, vol. 106, no. 1, pp. 23–34, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. E. Bernstein, S. Y. Kim, M. A. Carmell et al., “Dicer is essential for mouse development,” Nature Genetics, vol. 35, no. 3, pp. 215–217, 2003. View at Google Scholar
  8. J. J. D. Ho and P. A. Marsden, “Dicer cuts the kidney,” Journal of the American Society of Nephrology, vol. 19, no. 11, pp. 2043–2046, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Damiani, J. J. Alexander, J. R. O'Rourke et al., “Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina,” Journal of Neuroscience, vol. 28, no. 19, pp. 4878–4887, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. S. A. Georgi and T. A. Reh, “Dicer is required for the transition from early to late progenitor state in the developing mouse retina,” The Journal of Neuroscience, vol. 30, no. 11, pp. 4048–4061, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. T. R. Sundermeier, N. Zhang, F. Vinberg et al., “DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice,” The Journal of the Federation of American Societies of Experimental Biology, vol. 28, no. 8, pp. 3780–3791, 2004. View at Google Scholar
  12. H. Kaneko, S. Dridi, V. Tarallo et al., “DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration,” Nature, vol. 471, no. 7338, pp. 325–332, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. V. Tarallo, Y. Hirano, B. D. Gelfand et al., “DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88,” Cell, vol. 149, no. 4, pp. 847–859, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. X. Shu, Z. Zeng, P. Gautier et al., “Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes,” Human Molecular Genetics, vol. 19, no. 4, pp. 657–670, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. R. K. Raghupathy, D. L. McCulloch, S. Akhtar, T. M. Al-Mubrad, and X. Shu, “Zebrafish model for the genetic basis of X-linked retinitis pigmentosa,” Zebrafish, vol. 10, no. 1, pp. 62–69, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. E. de Bruijn, E. Cuppen, and H. Feitsma, “Highly efficient ENU mutagenesis in zebrafish,” Methods in Molecular Biology, vol. 546, pp. 3–12, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Tarboush, G. B. Chapman, and V. P. Connaughton, “Ultrastructure of the distal retina of the adult zebrafish, Danio rerio,” Tissue and Cell, vol. 44, no. 4, pp. 264–279, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Jaskiewicz and W. Filipowicz, “Role of Dicer in posttranscriptional RNA silencing,” Current Topics in Microbiology and Immunology, vol. 320, pp. 77–97, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. H. M. Stowe, E. Curry, S. M. Calcatera, R. L. Krisher, M. Paczkowski, and S. L. Pratt, “Cloning and expression of porcine Dicer and the impact of developmental stage and culture conditions on MicroRNA expression in porcine embryos,” Gene, vol. 501, no. 2, pp. 198–205, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Kanellopoulou, S. A. Muljo, A. L. Kung et al., “Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing,” Genes & Development, vol. 19, no. 4, pp. 489–501, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. E. Bernstein, S. Y. Kim, M. A. Carmell et al., “Dicer is essential for mouse development,” Nature Genetics, vol. 35, no. 3, pp. 215–217, 2003. View at Publisher · View at Google Scholar
  22. A. Iida, T. Shinoe, Y. Baba, H. Mano, and S. Watanabe, “Dicer plays essential roles for retinal development by regulation of survival and differentiation,” Investigative Ophthalmology and Visual Science, vol. 52, no. 6, pp. 3008–3017, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. A. La Torre, S. Georgi, and T. A. Reh, “Conserved microRNA pathway regulates developmental timing of retinal neurogenesis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 26, pp. E2362–E2370, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. A. J. Giraldez, R. M. Cinalli, M. E. Glasner et al., “MicroRNAs regulate brain morphogenesis in zebrafish,” Science, vol. 308, no. 5723, pp. 833–838, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. L. G. Fritsche, R. N. Fariss, D. Stambolian, G. R. Abecasis, C. A. Curcio, and A. Swaroop, “Age-related macular degeneration: genetics and biology coming together,” Annual Review of Genomics and Human Genetics, vol. 15, pp. 151–171, 2014. View at Publisher · View at Google Scholar
  26. J. L. Haines, M. A. Hauser, S. Schmidt et al., “Complement factor H variant increases the risk of age-related macular degeneration,” Science, vol. 308, no. 5720, pp. 419–421, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. R. J. Klein, C. Zeiss, E. Y. Chew et al., “Complement factor H polymorphism in age-related macular degeneration,” Science, vol. 308, no. 5720, pp. 385–389, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. A. O. Edwards, R. Ritter III, K. J. Abel, A. Manning, C. Panhuysen, and L. A. Farrer, “Complement factor H polymorphism and age-related macular degeneration,” Science, vol. 308, no. 5720, pp. 421–424, 2005. View at Publisher · View at Google Scholar · View at Scopus