Research Article

Gene Expression Profiling of the Optic Nerve Head of Patients with Primary Open-Angle Glaucoma

Table 1

The 31 significant DEGs between POAG ONH and normal ONH samples.

GenelogFC value

HIST1H2BE1.0856160.018774
ST13P40.8736230.00046
HIST1H2AJ0.7781740.025284
AGXT2L10.7747780.028185
PTGS20.717950.01722
ASPN0.7133620.030858
PSME20.658830.030883
ULBP10.6483970.031441
DPPA30.6360510.009133
FLJ375430.5943890.034072
ITGBL10.5853210.027386
FABP3−0.602660.014561
FSTL5−0.606420.00971
IMPG2−0.610990.027252
DNM1P41−0.615370.005843
RBP3−0.620180.017575
RARRES1−0.630460.02175
OR2M7−0.653310.02169
OR2V2−0.685670.000135
APIP−0.714790.03663
EYS−0.726940.025346
NEUROD1−0.729250.043711
OR13C9−0.748640.006745
GNAT2−0.748850.011052
IMPG1−0.778550.025706
UBQLN4−0.794550.017207
CLUL1−0.815030.037454
SUMO1P3−0.829120.015582
OR4N4−0.831760.013802
GUCA1C−0.873370.035767
OPN1LW−1.092610.009174

DEGs, differentially expressed genes; POAG, primary open-angle glaucoma; ONH, optic nerve head; FC, fold change.