Gene Expression Profiling of the Optic Nerve Head of Patients with Primary Open-Angle Glaucoma

Table 2

GO and KEGG pathway enrichment analysis of DEGs.

Category	Ontology/pathway	ID	Term	Gene count	value
POAG-UP	BP	GO:0006334	Nucleosome assembly	2	0.030668023
	BP	GO:0031497	Chromatin assembly	2	0.031749223
	BP	GO:0065004	Protein-DNA complex assembly	2	0.033189322
	BP	GO:0034728	Nucleosome organization	2	0.033908729
	CC	GO:0000786	Nucleosome	2	0.038767339
POAG-DOWN	BP	GO:0007600	Sensory perception	11	3.23E-09
	BP	GO:0050890	Cognition	11	9.87E-09
	BP	GO:0007601	Visual perception	7	1.08E-07
	BP	GO:0050953	Sensory perception of light stimulus	7	1.08E-07
	BP	GO:0050877	Neurological system process	11	1.53E-07
	REACTOME_PATHWAY	REACT_14797	Signaling by GPCR	5	0.005027711
	KEGG_PATHWAY	hsa04740	Olfactory transduction	5	8.87E-04

GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes; BP, biological process; CC, cellular component.