The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy
Table 1
Clinical characteristics of diabetes patients without diabetic retinopathy (NDR) and with mild nonproliferative diabetic retinopathy (NPDR).
All
NDR
Mild NPDR
value
Number of eyes
42
25
17
—
Number of patients
42
25
17
—
Age (years)
54.0 (20.8)
57.0 (16.0)
51.0 (26.0)
0.19
Sex (M : F)
26 : 16
15 : 10
11 : 6
1.00a
SBP (mmHg)
125.0 (10.0)
125.0 (10.0)
124.0 (10.0)
0.87
Diabetes duration (years)
5.5 (11.0)
4.0 (9.0)
10.0 (9.0)
0.04
Creatinine (mg/dl)
0.7 (0.3)
0.8 (0.3)
0.7 (0.3)
0.65
Total cholesterol (mg/dl)
185.5 (47.8)
186.0 (50.0)
185.0 (38.0)
0.80
HbA1c (%)
9.2 (1.9)
9.0 (1.8)
10.0 (1.5)
0.19
Carotid IMT
0.8 (0.3)
0.8 (0.2)
0.8 (0.3)
0.89
NCV
Median SCV (m/sec)
58.9 (8.5)
59.6 (6.0)
56.0 (10.5)
0.06
Median MCV (m/sec)
50.4 (6.0)
53.3 (5.8)
49.2 (2.9)
0.02
Sural SCV (m/sec)
49.6 (8.9)
50.8 (5.1)
47.2 (10.5)
0.008
Tibial MCV (m/sec)
42.5 (4.4)
43.2 (3.7)
41.0 (5.4)
0.01
VA (logMAR)
−0.08 (0.1)
−0.08 (0.08)
−0.08 (0.2)
0.67
SE (diopter)
−1.44 (2.7)
−0.75 (2.9)
−2.00 (3.0)
0.32
IOP (mmHg)
16.0 (4.8)
16.0 (5.0)
17.0 (4.0)
0.30
OCT finding
CMT (μm)
241.5 (36.5)
234 (26.0)
249 (23.0)
0.01
CT (μm)
265.3 (90.5)
248 (59.5)
291 (111.5)
0.10
NDR = no diabetic retinopathy, NPDR = nonproliferative diabetic retinopathy, SBP = systolic blood pressure, IMT = intima-media thickness, NCV = nerve conduction velocity, SCV = sensory conduction velocity, MCV = motor conduction velocity, VA = visual acuity, SE = spherical equivalent, IOP = intraocular pressure, CMT = central macular thickness, CT = choroidal thickness. Continuous variables are expressed as median (IQR). Unmarked value: Mann-Whitney U test; achi-square test.
