Research Article

Toxicity of Methylated Bismuth Compounds Produced by Intestinal Microorganisms to Bacteroides thetaiotaomicron, a Member of the Physiological Intestinal Microbiota

Figure 2

Growth inhibition of B. thetaiotaomicron 48 h after exposure of methylated bismuth species ( ). The addition of TMBi (a) to the headspace or of nonvolatile methylated bismuth species MMBi and DMBi (c) to the liquid phase of growing B. thetaiotaomicron cultures resulted in a growth reduction in a concentration-dependent manner. Figure 2(b) shows the growth curve in the presence of TMBi. The culture was separated in aliquots in the late exponential phase and was exposed to different TMBi concentrations. The cell counts were determined after 48 h at the stationary phase.
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