Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Table 2
The effects of different concentrations of methanolic extract of pomelo on the relative organ weight.
Organs
Control
250 mg/kg
500 mg/kg
1000 mg/kg
Heart
0.280 ± 0.01
0.278 ± 0.03
0.282 ± 0.03
0.300 ± 0.01
Kidney
0.589 ± 0.03
0.617 ± 0.01
0.645 ± 0.01
0.657 ± 0.06
Lung
0.548 ± 0.08
0.552 ± 0.10
0.549 ± 0.06
0.551 ± 0.13
Liver
3.060 ± 0.29
3.031 ± 0.18
3.309 ± 0.11
3.00 ± 1.43
Spleen
0.352 ± 0.05
0.368 ± 0.04
0.348 ± 0.03
0.360 ± 0.22
Caecum
0.352 ± 0.05
0.325 ± 0.45
0.347 ± 0.03
0.355 ± 0.07
Pancreas
0.165 ± 0.03
0.181 ± 0.10
0.162 ± 0.10
0.151 ± 0.04
Brain
0.811 ± 0.08
0.775 ± 0.00
0.804 ± 0.09
0.857 ± 0.15
Testes
0.072 ± 0.01
0.078 ± 0.02
0.077 ± 0.01
0.080 ± 0.00
Thymus
0.183 ± 0.01
0.139 ± 0.14
0.179 ± 0.03
0.167 ± 0.05
Caput
0.356 ± 0.09
0.408 ± 0.04
0.354 ± 0.03
0.346 ± 0.02
CPG
0.131 ± 0.01
0.129 ± 0.01
0.126 ± 0.00
0.122 ± 0.01
Stomach
0.620 ± 0.02
0.573 ± 0.22
0.692 ± 0.05
0.675 ± 0.14
Ovary
0.065 ± 0.02
0.067 ± 0.02
0.070 ± 0.01
0.062 ± 0.00
FT
0.263 ± 0.00
0.290 ± 0.05
0.270 ± 0.05
0.286 ± 0.05
Results are expressed as mean ± SD (n=8). CPG: Cowper gland and FT: fallopian tube. Nonsignificant changes were found when all treatment groups were compared against the control group (p< 0.05) as determined by using a one-way ANOVA followed by Dunnett’s multiple comparison tests. Table 2 is reproduced from Sudip Paul et al. (2017) [under the Creative Commons Attribution License/public domain].
