Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction
Table 4
Predictors of postinfarct left ventricular remodelling in univariate and multivariate analyses. Univariate analysis shows demographic, clinical, angiographic, biochemical, and discharge echocardiographic parameters from Tables 1–3 with a value <0.1 as well as BNP, CRP, and leukocyte count independently of their values, while results of multivariate analysis are restricted to variables with a value <0.05. Results are presented according to decreasing values of odds ratios.
Univariate analysis
OR
95% CI
CRP on admission (for a 10 mg/L increase)
2.99
0.60–14.92
NS
IRA: LAD versus non-LAD
1.92
1.02–3.63
<0.05
Anterior versus nonanterior wall STEMI
1.76
0.94–3.30
0.077
Diabetes mellitus
1.46
0.95–2.24
0.086
CRP 24 h after admission (for a 10 mg/L increase)
1.29
1.08–1.56
<0.01
TnImax (for a 10 ng/mL increase)
1.18
0.99–1.40
0.051
BNP at discharge (for a 100 pg/mL increase)
1.14
1.02–1.28
<0.05
Body mass index (for a 1 kg/m2 increase)
1.10
1.01–1.20
<0.05
Leukocyte count on admission (for a 103/L increase)
1.10
0.99–1.22
0.068
Leukocyte count 24 h after admission (for a 103/L increase)
1.09
0.97–1.23
NS
BNP on admission (for a 100 pg/mL increase)
1.08
0.88–1.33
NS
CK-MBmax (for a 10 U/L increase)
1.07
1.03–1.11
<0.001
CRP at discharge (for a 10 mg/L increase)
1.05
0.86–1.30
NS
Multivariate analysis
CRP 24 h after admission (for a 10 mg/L increase)
1.29
1.04–1.60
<0.05
BNP at discharge (for a 100 pg/mL increase)
1.21
1.05–1.39
<0.01
Body mass index (for a 1 kg/m2 increase)
1.10
1.01–1.21
<0.05
LVEDV at discharge (for a 1 mL increase)
0.98
0.96–0.99
<0.01
BNP: B-type natriuretic peptide; CI: confidence interval; CK-MBmax: maximal activity of izoenzyme MB of creatine kinase; CRP: C-reactive protein; IRA: infarct-related artery; LAD: left anterior descending artery; LVEDV: left ventricular end-diastolic volume; MI: myocardial infarction; NYHA: New York Heart Association; OR: odds ratio; STEMI: ST-segment elevation myocardial infarction; TnImax: maximal concentration of troponin I.
