Syk/Src Pathway-Targeted Inhibition of Skin Inflammatory Responses by Carnosic Acid

Figure 2

Effect of CA on the production of inflammatory cytokines and chemokines in HaCaT cells stimulated with SLS and RA. (a) and (b) Levels of IL-6, IL-8, and MCP-1 were determined by ELISA from culture supernatants of HaCaT cells treated with CA (0 to 10 μg/mL) or hydrocortisone (HC, 1 μg/mL) in the presence or absence of SLS (1 μg/mL) or RA (5 μM) for 24 h. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared to the control.

(a)

(b)