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Mediators of Inflammation
Volume 2013, Article ID 427021, 12 pages
Research Article

The Role of Mcl-1 in S. aureus-Induced Cytoprotection of Infected Macrophages

1Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Ul. Gronostajowa 7, 30-387 Kraków, Poland
2Broegelmann Research Laboratory, The Gade Institute, University of Bergen, 50021 Bergen, Norway
3Oral Health and Systemic Diseases Research Group, School of Dentistry, University of Louisville, Louisville, KY 40204, USA

Received 11 October 2012; Revised 7 December 2012; Accepted 10 December 2012

Academic Editor: Chiou-Feng Lin

Copyright © 2013 Joanna Koziel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure1. Clinical and bacteriological examination of S. aureus induced septic arthritis.

Supplementary Figure 2. Increased susceptibility to the spontaneous cell death in MCL1 knockdown macrophages infected with S. aureus.

Supplementary Figure 3. IL-6 secretion induced by S. aureus in hMDMs.

Supplementary Figure 4. NFκB activity induced by S. aureus in hMDMs.

  1. Supplementary Material