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Mediators of Inflammation
Volume 2014, Article ID 412386, 12 pages
http://dx.doi.org/10.1155/2014/412386
Research Article

Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study

1Health Management Centre, Tianjin Medical University General Hospital, Tianjin, China
2Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China

Received 21 November 2013; Accepted 2 April 2014; Published 29 April 2014

Academic Editor: Dianne Cooper

Copyright © 2014 Shaomei Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Lozano, M. Naghavi, K. Foreman et al., “Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010,” The Lancet, vol. 380, no. 9859, pp. 2095–2128, 2012. View at Google Scholar
  2. T. A. Pearson, G. A. Mensah, R. W. Alexander et al., “Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association,” Circulation, vol. 107, no. 3, pp. 499–511, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. N. S. Jenny, “Inflammation in aging: cause, effect, or both?” Discovery Medicine, vol. 13, no. 73, pp. 451–460, 2012. View at Google Scholar
  4. D. W. Kamp, E. Shacter, and S. A. Weitzman, “Chronic inflammation and cancer: the role of the mitochondria,” Oncology, vol. 25, no. 5, pp. 400–410, 413, 2011. View at Google Scholar · View at Scopus
  5. S. Sakuragi, J. Moriguchi, F. Ohashi, and M. Ikeda, “Reference value and annual trend of white blood cell counts among adult Japanese population,” Environmental Health and Preventive Medicine, vol. 18, no. 2, pp. 143–150, 2013. View at Google Scholar
  6. E. Oda and R. Kawai, “The prevalence of metabolic syndrome and diabetes increases through the quartiles of white blood cell count in Japanese men and women,” Internal Medicine, vol. 48, no. 13, pp. 1127–1134, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. D.-J. Kim, J.-H. Noh, B.-W. Lee et al., “The associations of total and differential white blood cell counts with obesity, hypertension, dyslipidemia and glucose intolerance in a Korean population,” Journal of Korean Medical Science, vol. 23, no. 2, pp. 193–198, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. Y.-Y. Wang, S.-Y. Lin, P.-H. Liu, B. M. H. Cheung, and W.-A. Lai, “Association between hematological parameters and metabolic syndrome components in a Chinese population,” Journal of Diabetes and its Complications, vol. 18, no. 6, pp. 322–327, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Odagiri, A. Uehara, I. Mizuta, M. Yamamoto, and C. Kurata, “Longitudinal study on white blood cell count and the incidence of metabolic syndrome,” Internal Medicine, vol. 50, no. 21, pp. 2491–2498, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. W. Meng, C. Zhang, Q. Zhang et al., “Association between leukocyte and metabolic syndrome in urban Han Chinese: a longitudinal cohort study,” PLoS ONE, vol. 7, no. 11, Article ID e49875, 2012. View at Google Scholar
  11. N. Babio, N. Ibarrola-Jurado, M. Bullo et al., “White blood cell counts as risk markers of developing metabolic syndrome and its components in the Predimed study,” PLoS ONE, vol. 8, no. 3, Article ID e58354, 2013. View at Google Scholar
  12. K. Tamakoshi, H. Toyoshima, H. Yatsuya et al., “White blood cell count and risk of all-cause and cardiovascular mortality in nationwide sample of Japanese—results from the NIPPON DATA90,” Circulation Journal, vol. 71, no. 4, pp. 479–485, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Song, H. Du, Q. Zhang et al., “Serum immunoglobulin M concentration is positively related to metabolic syndrome in an adult population: tianjin chronic low-grade systemic inflammation and health (TCLSIH) cohort study,” PLoS ONE, vol. 9, no. 2, Article ID e88701, 2014. View at Google Scholar
  14. “About Tianjin,” 2013http://www.tj.gov.cn/english/About_tianjin/Visiting_Tianjin/.
  15. G. Maresca, A. di Blasio, R. Marchioli, and G. di Minno, “Measuring plasma fibrinogen to predict stroke and myocardial infarction: an update,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 19, no. 6, pp. 1368–1377, 1999. View at Google Scholar · View at Scopus
  16. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., “Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; national heart, lung, and blood institute; American heart association; world heart federation; international atherosclerosis society; and international association for the study of obesity,” Circulation, vol. 120, no. 16, pp. 1640–1645, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Y. Chung, M. Cesari, S. Anton et al., “Molecular inflammation: underpinnings of aging and age-related diseases,” Ageing Research Reviews, vol. 8, no. 1, pp. 18–30, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. C. E. Lewis, K. M. McTigue, L. E. Burke et al., “Mortality, health outcomes, and body mass index in the overweight range: a science advisory from the american heart association,” Circulation, vol. 119, no. 25, pp. 3263–3271, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. F. Corre, J. Lellouch, and D. Schwartz, “Smoking and leucocyte-counts. Results of an epidemiological survey,” The Lancet, vol. 2, no. 7725, pp. 632–634, 1971. View at Google Scholar · View at Scopus
  20. J. B. Zalokar, J. L. Richard, and J. R. Claude, “Leukocyte count, smoking, and myocardial infarction,” The New England Journal of Medicine, vol. 304, no. 8, pp. 465–468, 1981. View at Google Scholar · View at Scopus
  21. E. Oda and R. Kawai, “Comparison between high-sensitivity C-reactive protein (hs-CRP) and white blood cell count (WBC) as an inflammatory component of metabolic syndrome in Japanese,” Internal Medicine, vol. 49, no. 2, pp. 117–124, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. Y. H. Kang, H. G. Min, I. J. Kim, Y. K. Kim, and S. M. Son, “Comparison of alanine aminotransferase, white blood cell count, and uric acid in their association with metabolic syndrome: a study of Korean adults,” Endocrine Journal, vol. 55, no. 6, pp. 1093–1102, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. G. P. Fadini, G. Marcuzzo, M. C. Marescotti, S. V. de Kreutzenbergand, and A. Avogaro, “Elevated white blood cell count is associated with prevalence and development of the metabolic syndrome and its components in the general population,” Acta Diabetologica, vol. 49, no. 6, pp. 445–451, 2012. View at Google Scholar
  24. N. Nakanishi, K. Suzuki, and K. Tatara, “White blood cell count and clustered features of metabolic syndrome in Japanese male office workers,” Occupational Medicine, vol. 52, no. 4, pp. 213–218, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. K. I. Kim, J. Lee, N. J. Heo et al., “Differential white blood cell count and all-cause mortality in the Korean elderly,” Experimental Gerontology, vol. 48, no. 2, pp. 103–108, 2013. View at Google Scholar
  26. K. Niu, A. Hozawa, H. Guo et al., “Serum C-reactive protein even at very low (<1.0 mg/l) concentration is associated with physical performance in a community-based elderly population aged 70 years and over,” Gerontology, vol. 54, no. 5, pp. 260–267, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Sun, Y. Ji, S. Kersten, and L. Qi, “Mechanisms of inflammatory responses in obese adipose tissue,” Annual Review of Nutrition, vol. 32, pp. 261–286, 2012. View at Google Scholar
  28. H. Sell and J. Eckel, “Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes,” Current Opinion in Clinical Nutrition and Metabolic Care, vol. 13, no. 4, pp. 366–370, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. C. Nathan, “Epidemic inflammation: pondering obesity,” Molecular Medicine, vol. 14, no. 7-8, pp. 485–492, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Calabrò, E. Golia, V. Maddaloni et al., “Adipose tissue-mediated inflammation: the missing link between obesity and cardiovascular disease?” Internal and Emergency Medicine, vol. 4, no. 1, pp. 25–34, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. W. Y. Hsu, C. H. Wu, C. T. Hsieh, H. C. Lo, J. S. Lin, and M. D. Kao, “Low body weight gain, low white blood cell count and high serum ferritin as markers of poor nutrition and increased risk for preterm delivery,” Asia Pacific Journal of Clinical Nutrition, vol. 22, no. 1, pp. 90–99, 2013. View at Google Scholar