Table 4: Association between CDH13 rs12051272 genotypes and adiposity status and adiponectin levels and inflammatory marker levels.

GenotypeGG ()GT ()TT ()Β (95% CI)P1P2P3

AnthropologyAge (years)44.6 ± 8.245.3 ± 10.544.8 ± 9.3
Body mass index (kg/m2)23.7 ± 3.024.4 ± 3.825.0 ± 3.80.0121.07 (0.12–2.02)0.027
Waist circumference (cm)83.5 ± 8.884.8 ± 10.088.3 ± 11.01.31 × 10−40.0040.0114.68 (2.17–7.19)2.71 × 10−40.0030.008
Adiponectin (mg/L)8.58 ± 5.446.40 ± 3.985.15 ± 4.382.7 × 10−107.45 × 10−9−0.20 (−0.27 to −0.13)2.57 × 10−83.52 × 10−7

Inflammation
marker
CRP (mg/L)1.10 ± 1.510.88 ± 1.061.44 ± 1.600.0180.1630.7020.18 (0.04–0.31)0.0100.0840.395
Fibrinogen (mg/dL)261.7 ± 71.6261.4 ± 62.8273.2 ± 79.70.2410.4630.64611.59 (−7.19–30.38)0.2260.4120.563
sE-selectin (ng/mL)52.8 ± 21.749.76 ± 20.7065.08 ± 47.160.0180.0830.3270.07 (0.02–0.12)0.0090.0390.160
sP-selectin (ng/mL)137.6 ± 104.8132.4 ± 119.7165.0 ± 137.70.0930.1160.2300.08 (−0.0004–0.16)0.0510.0640.126
sVCAM1 (ng/mL)485.9 ± 107.4479.2 ± 105.5537.6 ± 263.70.0270.0140.0010.03 (0.01–0.06)0.0190.0100.001
sICAM1 (ng/mL)236.8 ± 95.2235.3 ± 89.8286.1 ± 16.000.0240.058 0.1710.06 (0.01–0.11)0.0160.0370.103
sTNFR2 (pg/mL)3222.1 ± 900.73230.7 ± 939.53411.4 ± 964.80.1250.1940.1930.03 (−0.01–0.06)0.1210.1800.180
MCP1 (pg/mL)70.8 ± 61.679.1 ± 65.165.0 ± 33.20.9140.8450.844−0.02 (−0.10–0.06)0.6180.5640.558
IL6 (pg/L)4.7 ± 10.03.4 ± 4.74.8 ± 5.90.0650.1290.1650.12 (0.002–0.0.24)0.0460.2210.107
MMP1 (pg/mL)518.1 ± 1341.1472.0 ± 1174.5446.2 ± 675.80.2210.2320.2400.09 (−0.04–0.22)0.1860.1970.204
MMP2 (ng/mL)124.4 ± 35.4127.6 ± 44.7123.8 ± 46.00.7490.8630.877−0.02 (−0.05–0.02)0.3560.4370.748
MMP9 (ng/mL)145.9 ± 122.3139.2 ± 97.6156.5 ± 131.00.3590.5040.68516.37 (−15.44–48.19)0.3130.4290.574
SAA (mg/L)6.32 ± 13.925.35 ± 17.776.35 ± 11.800.6180.8650.5970.05 (−0.09–0.19)0.4620.6530.439

Abbreviations as in Table 1.
= number; CRP: excluded subjects with CRP levels >10 mg/L;   value adjusted for age and sex; value adjusted for age, sex, BMI, and smoking status; value further adjusted for adiponectin levels; sICAM1: only subjects with ICAM1 rs5491 AA genotype selected; data was analyzed in recessive model (GG + GTversus TT).