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Mediators of Inflammation
Volume 2016, Article ID 2989548, 9 pages
Review Article

M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b

1CNR-Institute of Cell Biology and Neurobiology, Via del Fosso di Fiorano 65, 00143 Rome, Italy
2Fondazione Santa Lucia, Via del Fosso di Fiorano 65, 00143 Rome, Italy
3Inflammation and Experimental Surgery Unit, CIBERehd, Biomedical Research Institute of Murcia (IMIB-Arrixaca), Clinical University Hospital Virgen de la Arrixaca, 30120 Murcia, Spain

Received 23 September 2016; Accepted 24 November 2016

Academic Editor: Joana Gonçalves

Copyright © 2016 Chiara Parisi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [4 citations]

The following is the list of published articles that have cited the current article.

  • Maria Concetta Geloso, Valentina Corvino, Elisa Marchese, Alessia Serrano, Fabrizio Michetti, and Nadia D’Ambrosi, “The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches,” Frontiers in Aging Neuroscience, vol. 9, 2017. View at Publisher · View at Google Scholar
  • Jinming Han, Robert A. Harris, and Xing-Mei Zhang, “An updated assessment of microglia depletion: current concepts and future directions,” Molecular Brain, vol. 10, no. 1, 2017. View at Publisher · View at Google Scholar
  • Elisabeth Eppler, Peter Yotovski, Nils Lannes, Samar Etemad, and Luis Filgueira, “Microglia at center stage: A comprehensive review about the versatile and unique residential macrophages of the central nervous system,” Oncotarget, vol. 8, no. 69, pp. 114393–114413, 2017. View at Publisher · View at Google Scholar
  • Amber Ou, Ben J. Gu, and James S. Wiley, “The scavenger activity of the human P2X7 receptor differs from P2X7 pore function by insensitivity to antagonists, genetic variation and sodium concentration: Relevance to inflammatory brain diseases,” Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018. View at Publisher · View at Google Scholar