Research Article
Anti-Inflammatory Effects of Hyperbaric Oxygenation during DSS-Induced Colitis in BALB/c Mice Include Changes in Gene Expression of HIF-1α, Proinflammatory Cytokines, and Antioxidative Enzymes
Table 2
Catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD) activity in the colon, MLN, and spleen during colitis and HBO2 treatment.
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| BALB/c mice at the age of 10–12 weeks were randomly assigned into 4 groups (/group): CTRL: control mice, CTRL + HBO2: control mice undergoing HBO2 (60 min/2.4 ATM, 2x/day, days 1–8), DSS: mice receiving DSS (5% w/v, days 1–7), and DSS + HBO2: DSS treated mice undergoing HBO2. Presented data (mean ± s.e.m.) are representative results from one experiment with min. five mice/group; was considered significant; statistically different from CTRL, ; #statistically different from DSS, ; †statistically different from CTRL + HBO2, . | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||