Review Article
The Role of Defensins in HIV Pathogenesis
Table 2
Cellular sources and tissue localization of selected β-defensins.
| | HBD1 | HBD2 | HBD3 | HBD4 | HBD5/6 | References |
| Cellular (primary) | Keratinocytes, kidney epithelial cells, airway epithelial cells, female reproductive tract epithelial cells, mammary epithelial cells | Keratinocytes, oral epithelial cells | keratinocytes, airway epithelial cells, oral epithelial cells | Keratinocytes, airway epithelial cells | | [28, 75, 128–134] | Cellular (also reported) | Monocytes, macrophages, dendritic cells | Monocytes, macrophages, dendritic cells | | Neutrophils | | Tissuea | Pancreas | Trachea, lung | Tonsil, skin | Lung, kidney, uterus, testis, gastric antrum | Epididymis |
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amRNA expression was identified in tissues but cellular source was not determined.
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