Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages

Figure 2

Effects of GG9, dexamethasone (dexa), and CLI-095 on the M1 macrophage phenotype as defined by CD80⁺/CCR2⁺ cells. Cells were activated and treated as described in the legend of Figure 1. Fluorescence quantification dot plots (a) are from a representative experiment. Bars represent the mean (±SEM) of CD80⁺/CCR2⁺cells (b) from 6 independent experiments. versus resting; versus LPS.

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(b)