Intra-Articular Cytokine Levels in Adolescent Patients after Anterior Cruciate Ligament Tear

Table 2

Correlations between clinical characteristics and cytokine levels in the synovial fluid of adolescents. Growth plate maturity and diagnosis are reported in Table 1. Lysholm score was calculated as described in Methods. Time elapsed between trauma and sample collection was considered as follows: acute: 0–48 h after injury; subacute: 3 days–3 months; chronic group: >3 months.

	IL-6	IL-8	TNF-α	IL-10	IL-1β	IL-1ra
Growth plate maturity	0.506	0.010	0.026	0.558	0.013	0.883
Time from trauma	0.139	0.086	0.265	0.384	0.791	0.166
Meniscal tear	0.371	0.689	0.751	0.055	0.012	0.031
Lysholm score	0.019	0.338	0.979	0.017	0.170	0.759

indicates values of that reached statistical significance as resulting from the generalized fitted model.