Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients

Table 4

Correlations between studied serum and urine markers and eGFR, diabetes duration, and HbA_1c concentrations.

Marker	eGFR (CKD-EPICr)		Diabetes duration		HbA1c		uACR
		value		value		value		value
Serum cystatin C	−0.72	<0.001^#	0.17	0.1	−0.05	0.7	0.21	0.08
Urine albumin	0.02	0.9	0.21	0.071	0.28	0.020^#	NA
Urine albumin/creatinine	−0.01	0.9	0.25	0.037^#	0.29	0.015^#	NA
Serum NGAL	−0.15	0.2	0.09	0.4	0.10	0.4	0.13	0.3
Urine NGAL	−0.06	0.6	0.19	0.1	0.24	0.048^#	0.39	<0.001^#
Urine NGAL/creatinine	−0.05	0.7	0.24	0.046^#	0.25	0.035^#	0.36	0.002^#
Urine KIM-1	0.11	0.4	−0.03	0.8	0.08	0.5	0.32	0.005^#
Urine KIM-1/creatinine	0.05	0.7	0.05	0.7	0.16	0.2	0.45	<0.001^#
Urine transferrin	−0.17	0.1	0.19	0.1	0.32	0.006^#	0.48	<0.001^#
Urine IgG	−0.14	0.2	0.27	0.016^#	0.33	0.005^#	0.61	<0.001^#
Serum uromodulin	0.16	0.2	0.06	0.6	0.03	0.8	−0.09	0.4
Urine uromodulin	0.08	0.5	−0.14	0.2	−0.35	0.002^#	−0.03	0.8
Urine uromodulin/creatinine	0.04	0.7	−0.12	0.3	−0.32	0.009^#	0.01	0.9

^#Statistically significant correlation. Abbreviations: see Table 1; NA: not applicable.