Chemokine Receptor 2 (CXCR2) Gene Variants and Their Association with Periodontal Bacteria in Patients with Chronic Periodontitis
Table 4
Distribution of CXCR2 haplotypes (arranged as genotypes) in CP patients and healthy nonperiodontitis controls.
Haplogenotypes
Controls
CP
value
OR (95% CI)
+785 +1208 +1440/+785 +1208 +1440
(%)
(%)
CTG/CTG
27 (15.8)
52 (15.8)
0.55
1.00 (0.60-1.66)
CTG/TCA
67 (39.2)
128 (38.6)
0.51
0.99 (0.68-1.44)
CTG/TCG
6 (3.5)
12 (3.6)
0.58
1.04 (0.38-2.82)
CTG/CCA
5 (2.9)
11 (3.3)
0.52
1.15 (0.39-3.36)
CTG/TTG
6 (3.5)
5 (1.5)
0.13
0.42 (0.13-1.41)
CTG/CCG
6 (3.5)
11 (3.3)
0.55
0.95 (0.35-2.62)
CTG/CTA
2 (1.2)
2 (0.6)
0.42
0.52 (0.07-3.70)
CTG/TTA
0 (0.0)
2 (0.6)
0.43
#
TCA/TCA
21 (12.3)
42 (12.8)
0.50
1.05 (0.60-1.83)
TCA/TCG
12 (7.0)
21 (6.4)
0.46
0.90 (0.43-1.88)
TCA/CCA
9 (5.3)
13 (4.0)
0.32
0.74 (0.31-1.77)
TCA/TTG
0 (0.0)
8 (2.4)
0.03
#
TCA/CCG
3 (1.8)
5 (1.5)
0.55
0.86 (0.20-3.66)
TCA/CTA
2 (1.2)
0 (0.0)
0.12
#
TCA/TTA
2 (1.2)
0 (0.0)
0.12
#
TCG/TCG
0 (0.0)
5 (1.5)
0.12
#
TCG/TTG
1 (0.6)
3 (0.9)
0.58
1.56 (0.16-15.15)
TCG/CCG
0 (0.0)
1 (0.3)
0.66
#
CCA/CCA
0 (0.0)
3 (0.9)
0.28
#
CCA/CCG
0 (0.0)
1 (0.3)
0.95
#
CCA/CTA
1 (0.6)
1 (0.3)
0.57
0.52 (0.03-8.34)
TTG/TTG
1 (0.6)
3 (0.9)
0.58
1.56 (0.16-15.15)
CI = confidential interval; CP = chronic periodontitis; = number of subjects; OR = odds ratio. by the Fisher exact test (without correction for multiple comparisons), but there is a low in both groups. #OR not calculated because of the presence of zero.
