Are There Any Common Genetic Risk Markers for Rheumatoid Arthritis and Periodontal Diseases? A Case-Control Study
Table 2
Demographical characteristics and periodontal conditions in relation to rheumatoid arthritis (RA) and periodontal disease (PD).
Variable
Probands without RA ()
RA patients
value
All ()
No/mild PD ()
Severe PD ()
I
II
III
IV
I vs. II
III vs. IV
Demographical and anamnestic parameters
Age (years) ()
<0.001
0.129
Female gender (%)
50
71.3
77.6
52
0.002
0.014
Current smoking (%)
20
24.8
21.1
36
0.005
0.102
Periodontal conditions (median (25th-75th IQR))
Plaque index (%)
38 (28.7-59.3)
38.1 (16.1-68)
27.8 (9.5-57.8)
66 (41.5-83.2)
0.372
<0.001
Bleeding on probing/tooth (%)
42.4 (23.6-62.9)
38.5 (19.1-68.8)
32.7 (17.8-62.5)
60 (35.6-89.9)
0.934
0.001
Bleeding on probing/tooth surface (%)
8.7 (4.8-19.8)
9.5 (3.9-22.7)
8.6 (3.5-16.8)
19 (8.9-39.9)
0.664
0.001
Probing depth (mm)
2.5 (2.3-2.8)
4 (3-5.5)
3.5 (2.9-5.5)
5.5 (4.3-7.5)
<0.001
<0.001
Clinical attachment loss (mm)
2.8 (2.6-3.2)
4.1 (3.2-5.9)
3.5 (3-5)
5.9 (4.7-8.8)
<0.001
<0.001
Missing teeth (except 8th)
2 (0-3.75)
5 (2-10)
4 (1-9.75)
9 (5.5-15.5)
<0.001
0.001
Proximal attachment loss of ≥5 mm in ≥30% of teeth present. Statistical comparisons were made by the chi-square test including Yates correction for categorical variables. Continuous variables were analyzed by the Mann–Whitney test and presented as median (25th/75th interquartiles (IQR); values not normally distributed) or Student’s -test and mean (standard deviation (SD); normal distribution).
