Are There Any Common Genetic Risk Markers for Rheumatoid Arthritis and Periodontal Diseases? A Case-Control Study

Table 4

Binary logistic regression analyses investigating the impact of G allele of rs1801275 (IL4Rα) and G allele of rs361525 (TNFα) on the incidence of rheumatoid arthritis.

Variables	Regression coefficient	Odds ratio	95% confidence interval		value
			Lower	Upper
IL4Rα (rs1801275)
Age	0.056	1.06	1.04	1.08	<0.001
Female gender	0.897	2.45	1.55	3.87	<0.001
Current smoker	0.841	2.32	1.48	3.64	<0.001
P.g. positive	0.655	1.93	1.18	3.13	0.008
G allele	0.336	1.40	0.79	2.47	0.248
TNFα (rs361525)
Age	0.056	1.06	1.04	1.08	<0.001
Female gender	0.887	2.43	1.54	3.84	<0.001
Current smoker	0.863	2.37	1.51	3.71	<0.001
P.g. positive	0.676	1.97	1.21	3.19	0.006
G allele	0.370	1.45	0.59	3.57	0.422

Age, gender, smoking status, and the occurrence of Porphyromonas gingivalis (P.g.) were considered as confounding factors.