CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study

Figure 2

Serum sCD28 levels in patients with T2DM and its association with DKD and related traits. (a) Owing to limited assay sensitivity, sCD28 was not detected in several patients (21% in the control group and 4% in the DKD group). (b) Comparison of serum sCD28 levels in male and female patients in the study population (). (c) Comparison of serum sCD28 levels in different age groups (). (d) Comparison of serum sCD28 levels in DKD and control groups. (e) Relationship between serum sCD28 levels and log-transformed eGFR (, ). (f) Relationship between serum sCD28 levels and log-transformed creatinine (, ). (g) Relationship between serum sCD28 levels and log-transformed urinary albuminuria excretion rate (, ). n.s. means not significant (); .

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