Real-Life Outcome in Multiple Sclerosis in the Czech Republic

Table 3

Marginal structural Cox model of the time to EDSS 4.

(a)

Analysis of Maximum Likelihood Estimates, IPTW weighted
Parameter		DF	Parameter Estimate	Standard Error	Chi-Square	Pr > ChiSq	Hazard Ratio
Treatment group	1	1	-0.32243	0.41160	0.6137	0.4334	0.724
Treatment group	2	1	0.03347	0.28204	0.0141	0.9055	1.034
Treatment group	3	1	-0.81062	0.45828	3.1288	0.0769	0.445

(b)

Analysis of Maximum Likelihood Estimates, unweighted
Parameter		DF	Parameter Estimate	Standard Error	Chi-Square	Pr > ChiSq	Hazard Ratio
Treatment group	1	1	-0.15071	0.31195	0.2334	0.6290	0.860
Treatment group	2	1	-0.31822	0.24403	1.7004	0.1922	0.727
Treatment group	3	1	-1.03244	0.42806	5.8173	0.0159	0.356