Changes in Amino Acid and Acylcarnitine Plasma Profiles for Distinguishing Patients with Multiple Sclerosis from Healthy Controls

Figure 1

Unsupervised PCA. (a) Contribution of principal components to the data variance. (b) Correlation between variables; solid colours mean a strong correlation, and many variables correlated with each other. (c) PC1 and PC2 explain 29.91% and 20.24% of the variance, respectively, among individuals in the data. The elliptical area is equal to 95% of the probability -distribution for observations in the control and MS groups. (d) The contribution of metabolites to the variance for PC1 and PC2. Met, Phe, and several acylcarnitines turned out to make the greatest contribution to the variance of the data.

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