Neural Plasticity / 2008 / Article / Fig 3

Research Article

Spontaneous Plasticity of Multineuronal Activity Patterns in Activated Hippocampal Networks

Figure 3

pACSF induces an NMDA-dependent persistent increase in , but not . The same data as Figures 1(c) and 1(d) and data of perfusion with pACSF in the presence of 50  M AP5 were analyzed with the (a), (b), % (c), and % (d) indices (Control, ; pACSF, ; pACSF+AP5, ). (a) and (b) pACSF-induced increase in persisted after replacement with normal ACSF, an effect that was prevented by AP5, whereas pACSF-induced increase in was recovered to the pre-pACSF baseline level after pACSF washout. (c) and (d) show that neither % nor % detected pACSF-induced plastic changes. Data are means ±SEMs.

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