Spontaneous Plasticity of Multineuronal Activity Patterns in Activated Hippocampal Networks
Figure 3
pACSF induces an NMDA-dependent persistent increase in , but not . The
same data as Figures 1(c) and 1(d) and data of perfusion with pACSF in the
presence of 50 M AP5 were
analyzed with the (a), (b), % (c), and %(d) indices
(Control, ; pACSF, ; pACSF+AP5, ). (a) and (b) pACSF-induced increase in persisted after replacement with normal ACSF, an effect that was prevented by
AP5, whereas pACSF-induced increase in was recovered to the pre-pACSF baseline level after pACSF washout. (c) and (d) show
that neither % nor % detected pACSF-induced
plastic changes. Data are means ±SEMs.
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