The Role of -Containing Kainate Receptors in Entorhinal Cortex Gamma Frequency Oscillations
Figure 5
ATPA-generated gamma
frequency oscillations in the MEC are reduced by application of the GLUK5 selective
antagonist, UBP302. (a) Extracellular field recordings showing 1
second epochs of activity (i) in the presence of 5 μM
ATPA and (ii) following application of 10 μM UBP302.
(b) Pooled power spectra (n = 4) produced from 60 second epochs of
extracellular field recorded data, showing a control recording (black),
recording in the presence of 5 μM
ATPA (blue), and application of 10 μM UBP302 (green). Scale bar represents 200 milliseconds and 100 μV.
