Research Article

The Role of G L U K 𝟓 -Containing Kainate Receptors in Entorhinal Cortex Gamma Frequency Oscillations

Figure 7

Blocking homomeric GLUK5-containing KARs effectively reduces power and amplitude of ATPA-generated gamma frequency oscillations in the MEC (a) Extracellular field recordings showing 1 second epochs of activity (i) in the presence of 5 μM ATPA and (ii) following application of 15 μM NS3763. (b) Pooled power spectra (n = 4) produced from 60 second epochs of extracellular field recorded data, showing a control recording (black), recording in the presence of 5 μM ATPA (blue), and application of 15 μM NS3763 (green). Scale bar represents 200 milliseconds and 100 μV.
401645.fig.007a
(a)
401645.fig.007b
(b)