Sensory Deprivation during Early Postnatal Period Alters the Density of Interneurons in the Mouse Prefrontal Cortex

Figure 7

Sensory deprivation changes CR neuron density in the PFC. The density of CR neurons in the PL (a, b), IL (c, d), and dAC (e, f). CR neuron density at P28 (a, c, e) and P58 (b, d, f) in each area are shown. (a)-(b) There was no effect of sensory deprivation on the density of CR neurons in the PFC at P28. The density of CR neurons in L2/3 was increased by sensory deprivation at P56. (c)-(d) At P56 the density of CR neurons in L2/3 was increased by whisker trimming and dark rearing. (e)-(f) The density of CR neurons in L2/3 was increased by sensory deprivation at P56. Data are expressed as mean density S.E.M. ( per group). Abbreviations are the same as in Figure 4. compared with intact mice.

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